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FMN/FHY riboflavin kinase/FMN hydrolase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828232, updated on 18-Sep-2024

Summary

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Official Symbol
FMN/FHY
Official Full Name
riboflavin kinase/FMN hydrolase
Primary source
TAIR:AT4G21470
Locus tag
AT4G21470
See related
Araport:AT4G21470
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATFMN/FHY; F18E5.90; F18E5_90; riboflavin kinase/FMN hydrolase
Summary
Bifunctional enzyme that catalyzes hydrolysis of FMN to riboflavin, and phosphorylation of riboflavin to FMN.
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Genomic context

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See FMN/FHY in Genome Data Viewer
Location:
chromosome: 4
Exon count:
10
Sequence:
Chromosome: 4; NC_003075.7 (11431104..11433322)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene PapD-like superfamily protein Neighboring gene Ribosomal protein S24/S35 Neighboring gene sugar transporter protein 12 Neighboring gene NAD(P)H dehydrogenase B3 Neighboring gene ncRNA Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An FMN hydrolase is fused to a riboflavin kinase homolog in plants. Sandoval FJ, et al. J Biol Chem, 2005 Nov 18. PMID 16183635
  2. Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. Popescu SC, et al. Proc Natl Acad Sci U S A, 2007 Mar 13. PMID 17360592, Free PMC Article
  3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_118267.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables FMN adenylyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables riboflavin kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in FMN biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in riboflavin biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
riboflavin kinase/FMN hydrolase
NP_193878.2
  • riboflavin kinase/FMN hydrolase (FMN/FHY); FUNCTIONS IN: riboflavin kinase activity, FMN adenylyltransferase activity; INVOLVED IN: riboflavin biosynthetic process, metabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), Haloacid dehydrogenase/epoxide hydrolase (InterPro:IPR005833), Riboflavin kinase (InterPro:IPR015865), HAD-superfamily hydrolase, subfamily IA, variant 3 (InterPro:IPR006402); BEST Arabidopsis thaliana protein match is: Haloacid dehalogenase-like hydrolase (HAD) superfamily protein (TAIR:AT5G57440.1); Has 19964 Blast hits to 19956 proteins in 2653 species: Archae - 146; Bacteria - 15844; Metazoa - 398; Fungi - 526; Plants - 433; Viruses - 3; Other Eukaryotes - 2614 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    11431104..11433322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118267.5 → NP_193878.2  riboflavin kinase/FMN hydrolase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_193878.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65412, Q84MD8
    UniProtKB/TrEMBL
    A0A178V341, A0A5S9XVC6, A0A654FRF1
    Conserved Domains (1) summary
    PLN02940
    Location:1 → 379
    PLN02940; riboflavin kinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q84MD8.1

Gene LinkOut

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