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ABCB2 P-glycoprotein 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828702, updated on 18-Sep-2024

Summary

Official Symbol
ABCB2
Official Full Name
P-glycoprotein 2
Primary source
TAIR:AT4G25960
Locus tag
AT4G25960
See related
Araport:AT4G25960
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATP-binding cassette B2; F20B18.70; F20B18_70; P-glycoprotein 2; PGP2
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Genomic context

See ABCB2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
13
Sequence:
Chromosome: 4; NC_003075.7 (13177356..13183692)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ENTH/ANTH/VHS superfamily protein Neighboring gene vacuolar ATP synthase G3 Neighboring gene phosphatidylserine decarboxylase 3 Neighboring gene peroxidase superfamily protein Neighboring gene CCT motif family protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_118729.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
 
located_in cytosol HDA PubMed 

General protein information

Preferred Names
P-glycoprotein 2
NP_194326.2
  • P-glycoprotein 2 (PGP2); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 10 (TAIR:AT1G10680.1); Has 857619 Blast hits to 396855 proteins in 4207 species: Archae - 14871; Bacteria - 670687; Metazoa - 17931; Fungi - 12963; Plants - 9451; Viruses - 35; Other Eukaryotes - 131681 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    13177356..13183692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118729.4NP_194326.2  P-glycoprotein 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194326.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O04711, Q0WUR0, Q8LPK2
    UniProtKB/TrEMBL
    A0A654FST2
    Conserved Domains (3) summary
    cd03249
    Location:10301268
    ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
    PTZ00265
    Location:761269
    PTZ00265; multidrug resistance protein (mdr1); Provisional
    pfam00664
    Location:86349
    ABC_membrane; ABC transporter transmembrane region