GAMT1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: GAMT1
Official Full Name: S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
Primary source: TAIR:AT4G26420
Locus tag: AT4G26420
See related: Araport:AT4G26420
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtGAMT1; gibberellin methyltransferase 1; M3E9.150; M3E9_150
Summary: A member of the Arabidopsis SABATH methyltransferase gene family. Encodes GAMT1, a methyltransferase that uses S-adenosine-L-methionine (SAM) as a methyl donor to methylate the carboxyl group of GAs, resulting in the methyl esters of GAs (MeGAs). Expressed most highly in the siliques during seed development.
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Genomic context

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See GAMT1 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 3

Sequence:: Chromosome: 4; NC_003075.7 (13350796..13352569, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Tomato plants overexpressing AtGAMT1 exhibited typical GA-deficiency phenotypes and increased tolerance to drought stress.
Title: The Arabidopsis gibberellin methyl transferase 1 suppresses gibberellin activity, reduces whole-plant transpiration and promotes drought tolerance in transgenic tomato.
GAMT1 and GAMT2 encode enzymes that use S-adenosine-L-methionine (SAM) as a methyl donor to methylate the carboxyl group of GAs. Both genes are expressed most highly in the siliques during seed development. [GAMT1]
Title: Methylation of gibberellins by Arabidopsis GAMT1 and GAMT2.

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Pathways from PubChem

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General gene information

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NM_001125589.5

Supported by ESTs:

NM_001341798.1

Supported by ESTs:

NM_118775.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables S-adenosylmethionine-dependent methyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables gibberellin A9 carboxyl methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables gibberellin carboxyl-O-methyltransferase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: S-adenosyl-L-methionine-dependent methyltransferases superfamily protein

NP_001119061.1

GAMT1; CONTAINS InterPro DOMAIN/s: SAM dependent carboxyl methyltransferase (InterPro:IPR005299); BEST Arabidopsis thaliana protein match is: gibberellic acid methyltransferase 2 (TAIR:AT5G56300.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NP_194372.2

GAMT1; CONTAINS InterPro DOMAIN/s: SAM dependent carboxyl methyltransferase (InterPro:IPR005299); BEST Arabidopsis thaliana protein match is: gibberellic acid methyltransferase 2 (TAIR:AT5G56300.1); Has 916 Blast hits to 905 proteins in 122 species: Archae - 0; Bacteria - 67; Metazoa - 9; Fungi - 3; Plants - 723; Viruses - 0; Other Eukaryotes - 114 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

13350796..13352569 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_118775.3 → NP_194372.2 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_194372.2

Status: REVIEWED

UniProtKB/Swiss-Prot

B3H6L1, F4JUY5, O65592, Q56Z47

UniProtKB/TrEMBL

A0A5S9XW22, A0A654FT19

Conserved Domains (1) summary

pfam03492
Location:43 → 371

Methyltransf_7; SAM dependent carboxyl methyltransferase
NM_001125589.5 → NP_001119061.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001119061.1

Status: REVIEWED

UniProtKB/Swiss-Prot

F4JUY5

Conserved Domains (1) summary

pfam03492
Location:31 → 245

Methyltransf_7; SAM dependent carboxyl methyltransferase
NM_001341798.1 → NP_001329462.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B7R9