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PPX1 protein phosphatase X 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828779, updated on 18-Sep-2024

Summary

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Official Symbol
PPX1
Official Full Name
protein phosphatase X 1
Primary source
TAIR:AT4G26720
Locus tag
AT4G26720
See related
Araport:AT4G26720
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F10M23.60; F10M23_60; PPX-1; protein phosphatase X 1; PROTEIN PHOSPHATASE X-1
Summary
Encodes catalytic subunit of protein phosphatase X. Expressed at very low levels in A. thaliana flowers, leaves, stems and roots.
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Genomic context

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See PPX1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
8
Sequence:
Chromosome: 4; NC_003075.7 (13470030..13472486, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene DNA binding / DNA topoisomerase type I Neighboring gene ATPase, V0 complex, subunit E Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene peroxygenase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HIGH CROSSOVER RATE1 encodes PROTEIN PHOSPHATASE X1 and restricts meiotic crossovers in Arabidopsis. Nageswaran DC, et al. Nat Plants, 2021 Apr. PMID 33846593, Free PMC Article
  2. Identification and molecular cloning of two homologues of protein phosphatase X from Arabidopsis thaliana. Pérez-Callejón E, et al. Plant Mol Biol, 1993 Dec. PMID 8292782
  3. The Protein Phosphatase 4 and SMEK1 Complex Dephosphorylates HYL1 to Promote miRNA Biogenesis by Antagonizing the MAPK Cascade in Arabidopsis. Su C, et al. Dev Cell, 2017 Jun 5. PMID 28586645
  4. PLATINUM SENSITIVE 2 LIKE impacts growth, root morphology, seed set, and stress responses. Kataya ARA, et al. PLoS One, 2017. PMID 28678890, Free PMC Article
  5. The PP2A regulatory subunit Tap46, a component of the TOR signaling pathway, modulates growth and metabolism in plants. Ahn CS, et al. Plant Cell, 2011 Jan. PMID 21216945, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. HIGH CROSSOVER RATE1 encodes PROTEIN PHOSPHATASE X1 and restricts meiotic crossovers in Arabidopsis.
    Title: HIGH CROSSOVER RATE1 encodes PROTEIN PHOSPHATASE X1 and restricts meiotic crossovers in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_118806.6

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein serine/threonine phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein serine/threonine phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within protein dephosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
acts_upstream_of_or_within reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase X 1
NP_194402.1
  • protein phosphatase X 1 (PPX1); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: protein phosphatase X 2 (TAIR:AT5G55260.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    13470030..13472486 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118806.6 → NP_194402.1  protein phosphatase X 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194402.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P48529
    UniProtKB/TrEMBL
    A0A178V0Q8, A0A5S9XWI6
    Conserved Domains (1) summary
    cd07415
    Location:3 → 287
    MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P48529.1

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