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SLAH2 SLAC1 homologue 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828910, updated on 18-Sep-2024

Summary

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Official Symbol
SLAH2
Official Full Name
SLAC1 homologue 2
Primary source
TAIR:AT4G27970
Locus tag
AT4G27970
See related
Araport:AT4G27970
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
SLAC1 homologue 2; T13J8.80; T13J8_80
Summary
Encodes a protein with ten predicted transmembrane helices. The SLAH2 protein has similarity to the SLAC1 protein involved in ion homeostasis in guard cells. But, it is not expressed in guard cells and cannot complement a slac1-2 mutant suggesting that it performs a different function. SLAH2:GFP localizes to the plasma membrane.
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Genomic context

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See SLAH2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
4
Sequence:
Chromosome: 4; NC_003075.7 (13918165..13920378, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ubiquitin conjugating enzyme 9 Neighboring gene trichohyalin-like protein (DUF3444) Neighboring gene YGGT family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CO2 regulator SLAC1 and its homologues are essential for anion homeostasis in plant cells. Negi J, et al. Nature, 2008 Mar 27. PMID 18305482
  2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
  3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001341891.1
NM_001341892.1
NM_001341893.1
NM_001341894.1
NM_001341895.1
NM_118935.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables voltage-gated monoatomic anion channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular monoatomic ion homeostasis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
SLAC1 homologue 2
NP_001320078.1
  • SLAC1 homologue 2 (SLAH2); FUNCTIONS IN: transporter activity; INVOLVED IN: transmembrane transport; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: C4-dicarboxylate transporter/malic acid transport protein (InterPro:IPR004695); BEST Arabidopsis thaliana protein match is: SLAC1 homologue 3 (TAIR:AT5G24030.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    13918165..13920378 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001341891.1 → NP_001320078.1  SLAC1 homologue 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ASQ7, Q9SUE2
    UniProtKB/TrEMBL
    A0A178V1C3, A0A5S9XWI7
    Conserved Domains (1) summary
    cd09323
    Location:142 → 445
    TDT_SLAC1_like; Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes SLAC1 (Slow Anion Channel-Associated 1)

  2. NM_001341892.1 → NP_001328003.1  SLAC1 homologue 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B3D9

  3. NM_001341893.1 → NP_001328004.1  SLAC1 homologue 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B3E4

  4. NM_118935.3 → NP_567792.1  SLAC1 homologue 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567792.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ASQ7, Q9SUE2
    UniProtKB/TrEMBL
    A0A178V1C3, A0A5S9XWI7
    Conserved Domains (1) summary
    cd09323
    Location:142 → 445
    TDT_SLAC1_like; Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes SLAC1 (Slow Anion Channel-Associated 1)

  5. NM_001341894.1 → NP_001328005.1  SLAC1 homologue 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B3D9

  6. NM_001341895.1 → NP_001328006.1  SLAC1 homologue 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B3E4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ASQ7.1

Gene LinkOut

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