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AAC3 ADP/ATP carrier 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828955, updated on 18-Sep-2024

Summary

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Official Symbol
AAC3
Official Full Name
ADP/ATP carrier 3
Primary source
TAIR:AT4G28390
Locus tag
AT4G28390
See related
Araport:AT4G28390
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ADP/ATP carrier 3; ATAAC3; F20O9.60; F20O9_60
Summary
Encodes a mitochondrial ADP/ATP carrier protein. Shown in heterologous systems to be located in the plasma membrane. Has comparable affinity for ADP and ATP (in E.coli).
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Genomic context

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See AAC3 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
5
Sequence:
Chromosome: 4; NC_003075.7 (14041288..14043347, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene Leucine-rich repeat (LRR) family protein Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene non-specific lipid-transfer-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids. Haferkamp I, et al. Eur J Biochem, 2002 Jul. PMID 12084057
  2. The Arabidopsis class II sirtuin is a lysine deacetylase and interacts with mitochondrial energy metabolism. König AC, et al. Plant Physiol, 2014 Mar. PMID 24424322, Free PMC Article
  3. Interactomics of Qa-SNARE in Arabidopsis thaliana. Fujiwara M, et al. Plant Cell Physiol, 2014 Apr. PMID 24556609
  4. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931
  5. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001341915.1
NM_118980.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP:ADP antiporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATP:ADP antiporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in mitochondrial ADP transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial ATP transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within purine nucleotide transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast envelope HDA PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
ADP/ATP carrier 3
NP_194568.1
  • ADP/ATP carrier 3 (AAC3); FUNCTIONS IN: binding, ATP:ADP antiporter activity; INVOLVED IN: transport, mitochondrial transport, purine nucleotide transport; LOCATED IN: mitochondrion, mitochondrial inner membrane, membrane, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial carrier protein (InterPro:IPR002067), Mitochondrial substrate carrier (InterPro:IPR001993), Mitochondrial substrate/solute carrier (InterPro:IPR018108), Adenine nucleotide translocator 1 (InterPro:IPR002113); BEST Arabidopsis thaliana protein match is: ADP/ATP carrier 2 (TAIR:AT5G13490.2); Has 20286 Blast hits to 12392 proteins in 480 species: Archae - 0; Bacteria - 0; Metazoa - 9416; Fungi - 5054; Plants - 3787; Viruses - 0; Other Eukaryotes - 2029 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    14041288..14043347 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118980.4 → NP_194568.1  ADP/ATP carrier 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194568.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49447, Q8L9Y1
    UniProtKB/TrEMBL
    A0A178V026, A0A5S9XWM8
    Conserved Domains (1) summary
    PTZ00169
    Location:77 → 366
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  2. NM_001341915.1 → NP_001328166.1  ADP/ATP carrier 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49447, Q8L9Y1
    UniProtKB/TrEMBL
    A0A178V026, A0A5S9XWM8
    Conserved Domains (1) summary
    PTZ00169
    Location:77 → 366
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O49447.1

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