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DBR1 debranching enzyme 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829305, updated on 11-Oct-2024

Summary

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Official Symbol
DBR1
Official Full Name
debranching enzyme 1
Primary source
TAIR:AT4G31770
Locus tag
AT4G31770
See related
Araport:AT4G31770
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA DEBRANCHING ENZYME 1; ATDBR1; debranching enzyme 1; F28M20.40; F28M20_40
Summary
Encodes a RNA lariat debranching enzyme required for embryogenesis.
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Genomic context

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See DBR1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Sequence:
Chromosome: 4; NC_003075.7 (15370061..15372942, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Sec1/munc18-like (SM) proteins superfamily Neighboring gene HOPW1-1-interacting 2 Neighboring gene peroxidase superfamily protein Neighboring gene monogalactosyl diacylglycerol synthase 1 Neighboring gene Tetrapyrrole (Corrin/Porphyrin) Methylase Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequestration of DBR1 to stress granules promotes lariat intronic RNAs accumulation for heat-stress tolerance. Wu C, et al. Nat Commun, 2024 Sep 3. PMID 39227617, Free PMC Article
  2. An Arabidopsis RNA lariat debranching enzyme is essential for embryogenesis. Wang H, et al. J Biol Chem, 2004 Jan 9. PMID 14570879
  3. Intron Lariat RNA Inhibits MicroRNA Biogenesis by Sequestering the Dicing Complex in Arabidopsis. Li Z, et al. PLoS Genet, 2016 Nov. PMID 27870853, Free PMC Article
  4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

General gene information

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NM_001342112.1
NM_119326.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables RNA lariat debranching enzyme activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
debranching enzyme 1
NP_567881.1
  • debranching enzyme 1 (DBR1); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Lariat debranching enzyme, C-terminal (InterPro:IPR007708); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    15370061..15372942 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119326.4 → NP_567881.1  debranching enzyme 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567881.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O81771, Q94K01
    UniProtKB/TrEMBL
    A0A178V4L6, A0A384KTP8, A0A5S9XXQ3, A0A654FUL9, Q0D241
    Conserved Domains (2) summary
    cd00844
    Location:3 → 259
    MPP_Dbr1_N; Dbr1 RNA lariat debranching enzyme, N-terminal metallophosphatase domain
    pfam05011
    Location:241 → 352
    DBR1; Lariat debranching enzyme, C-terminal domain

  2. NM_001342112.1 → NP_001328612.1  debranching enzyme 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B568, A0A5S9XXQ3, A0A654FUL9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q94K01.1

Gene LinkOut

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