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CER4 Jojoba acyl CoA reductase-related male sterility protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829521, updated on 18-Sep-2024

Summary

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Official Symbol
CER4
Official Full Name
Jojoba acyl CoA reductase-related male sterility protein
Primary source
TAIR:AT4G33790
Locus tag
AT4G33790
See related
Araport:AT4G33790
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ECERIFERUM 4; FAR3; FATTY ACID REDUCTASE 3; G7
Summary
Encodes an alcohol-forming fatty acyl-CoA reductase, involved in cuticular wax biosynthesis. Lines carrying recessive mutations are deficient in primary alcohol and have glossy stem surfaces.
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Genomic context

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See CER4 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
10
Sequence:
Chromosome: 4; NC_003075.7 (16204096..16207956, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ATP phosphoribosyltransferase regulatory subunit Neighboring gene uncharacterized protein Neighboring gene Glycosyl hydrolase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CER4 encodes an alcohol-forming fatty acyl-coenzyme A reductase involved in cuticular wax production in Arabidopsis. Rowland O, et al. Plant Physiol, 2006 Nov. PMID 16980563, Free PMC Article
  2. Chrysotile asbestos and health in Zimbabwe: I. Analysis of miners and millers compensated for asbestos-related diseases since independence (1980). Cullen MR, et al. Am J Ind Med, 1991. PMID 1847001
  3. Functional expression of five Arabidopsis fatty acyl-CoA reductase genes in Escherichia coli. Doan TT, et al. J Plant Physiol, 2009 May 15. PMID 19062129
  4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
  5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001342233.1
NM_119537.7

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables alcohol-forming long-chain fatty acyl-CoA reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within wax biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Jojoba acyl CoA reductase-related male sterility protein
NP_567936.5
  • ECERIFERUM 4 (CER4); FUNCTIONS IN: oxidoreductase activity, acting on the CH-CH group of donors, fatty-acyl-CoA reductase (alcohol-forming) activity; INVOLVED IN: microsporogenesis, wax biosynthetic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Male sterility (InterPro:IPR004262), NAD(P)-binding domain (InterPro:IPR016040), Male sterility, NAD-binding (InterPro:IPR013120); BEST Arabidopsis thaliana protein match is: fatty acid reductase 1 (TAIR:AT5G22500.1); Has 2106 Blast hits to 2074 proteins in 384 species: Archae - 24; Bacteria - 471; Metazoa - 997; Fungi - 134; Plants - 291; Viruses - 0; Other Eukaryotes - 189 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    16204096..16207956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119537.7 → NP_567936.5  Jojoba acyl CoA reductase-related male sterility protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567936.5

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O81895, Q93ZB9, Q9M071
    UniProtKB/TrEMBL
    A0A178V2G4, A0A5S9XYD2
    Conserved Domains (1) summary
    PLN02996
    Location:6 → 493
    PLN02996; fatty acyl-CoA reductase

  2. NM_001342233.1 → NP_001329220.1  Jojoba acyl CoA reductase-related male sterility protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V3Q9, A0A1P8B726
    Conserved Domains (1) summary
    PLN02996
    Location:1 → 380
    PLN02996; fatty acyl-CoA reductase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q93ZB9.1

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