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CPK18 calcium-dependent protein kinase 18 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829763, updated on 18-Sep-2024

Summary

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Official Symbol
CPK18
Official Full Name
calcium-dependent protein kinase 18
Primary source
TAIR:AT4G36070
Locus tag
AT4G36070
See related
Araport:AT4G36070
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
calcium-dependent protein kinase 18; T19K4.200; T19K4_200
Summary
member of Calcium Dependent Protein Kinase
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Genomic context

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See CPK18 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
12
Sequence:
Chromosome: 4; NC_003075.7 (17056587..17059706, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene endonuclease/exonuclease/phosphatase family protein Neighboring gene ncRNA Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene phosphotransferases/inositol or phosphatidylinositol kinase Neighboring gene oxidoreductase, 2OG-Fe(II) oxygenase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-Wide Identification and Characterization of Calcium Metabolism Related Gene Families in Arabidopsis thaliana and Their Regulation by Bacillus amyloliquefaciens Under High Calcium Stress. Gong J, et al. Front Plant Sci, 2021. PMID 34456948, Free PMC Article
  2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

General gene information

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NM_001204003.1
NM_119774.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in response to calcium ion IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
calcium-dependent protein kinase 18
NP_001190932.1
  • calcium-dependent protein kinase 18 (CPK18); FUNCTIONS IN: protein serine/threonine kinase activity, calmodulin-dependent protein kinase activity, protein kinase activity, calcium ion binding, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: sperm cell, male gametophyte; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 16 (TAIR:AT2G17890.1).
NP_195331.2
  • calcium-dependent protein kinase 18 (CPK18); FUNCTIONS IN: protein serine/threonine kinase activity, calmodulin-dependent protein kinase activity, protein kinase activity, ATP binding, calcium ion binding; INVOLVED IN: protein amino acid phosphorylation, N-terminal protein myristoylation; EXPRESSED IN: sperm cell, male gametophyte; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 16 (TAIR:AT2G17890.1); Has 123753 Blast hits to 121604 proteins in 3839 species: Archae - 181; Bacteria - 14516; Metazoa - 45843; Fungi - 14448; Plants - 26576; Viruses - 602; Other Eukaryotes - 21587 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    17056587..17059706 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119774.3 → NP_195331.2  calcium-dependent protein kinase 18 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195331.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65644, Q1PE17
    UniProtKB/TrEMBL
    A0A5S9XZF5, A0A654FW12
    Conserved Domains (4) summary
    PTZ00184
    Location:367 → 514
    PTZ00184; calmodulin; Provisional
    smart00220
    Location:71 → 331
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd00051
    Location:459 → 513
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd05117
    Location:70 → 330
    STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases

  2. NM_001204003.1 → NP_001190932.1  calcium-dependent protein kinase 18 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190932.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V2V6, A0A5S9XZF5, A0A654FW12, F4JNY4
    Conserved Domains (4) summary
    PTZ00184
    Location:367 → 514
    PTZ00184; calmodulin; Provisional
    smart00220
    Location:71 → 331
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd00051
    Location:459 → 513
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd05117
    Location:70 → 330
    STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1PE17.1

Gene LinkOut

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