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basic helix-loop-helix (bHLH) DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829941, updated on 18-Sep-2024

Summary

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Official Full Name
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Primary source
TAIR:AT4G37850
Locus tag
AT4G37850
See related
Araport:AT4G37850
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T28I19.130; T28I19_130
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Genomic context

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Location:
chromosome: 4
Exon count:
5
Sequence:
Chromosome: 4; NC_003075.7 (17796072..17797901, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene hexokinase-like 3 Neighboring gene SPT2 chromatin protein Neighboring gene phosphoenolpyruvate carboxykinase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Arabidopsis bHLH25 and bHLH27 transcription factors contribute to susceptibility to the cyst nematode Heterodera schachtii. Jin J, et al. Plant J, 2011 Jan. PMID 21223395
  2. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Heim MA, et al. Mol Biol Evol, 2003 May. PMID 12679534
  3. Transcriptional regulation of nitrogen-associated metabolism and growth. Gaudinier A, et al. Nature, 2018 Nov. PMID 30356219
  4. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137
  5. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Two Arabidopsis basic helix-loop-helix transcription factors bHLH25 and bHLH27 positively influence cyst nematode parasitism.
    Title: The Arabidopsis bHLH25 and bHLH27 transcription factors contribute to susceptibility to the cyst nematode Heterodera schachtii.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001342458.1
NM_119946.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NP_195498.3
  • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT2G22750.2); Has 2910 Blast hits to 2902 proteins in 174 species: Archae - 4; Bacteria - 2; Metazoa - 77; Fungi - 51; Plants - 2768; Viruses - 0; Other Eukaryotes - 8 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    17796072..17797901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119946.4 → NP_195498.3  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195498.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8S3F0, Q9T072
    UniProtKB/TrEMBL
    A0A178UTY6, A0A5S9XZM3
    Conserved Domains (1) summary
    cd11452
    Location:148 → 222
    bHLH_AtNAI1_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana protein NAI1 and similar proteins

  2. NM_001342458.1 → NP_001329767.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8S3F0, Q9T072
    UniProtKB/TrEMBL
    A0A178UTY6, A0A5S9XZM3
    Conserved Domains (1) summary
    cd11452
    Location:148 → 222
    bHLH_AtNAI1_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana protein NAI1 and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9T072.2

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