U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GCP2 gamma-tubulin complex protein 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830445, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
GCP2
Official Full Name
gamma-tubulin complex protein 2
Primary source
TAIR:AT5G05620
Locus tag
AT5G05620
See related
Araport:AT5G05620
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA GAMMA-TUBULIN COMPLEX PROTEIN 2; ARABIDOPSIS THALIANA GAMMA-TUBULIN COMPLEX PROTEIN 2; ATGCP2; gamma-tubulin complex protein 2; GAMMA-TUBULIN 2; gamma-tubulin complex protein 2; MJJ3.10; MJJ3_10; TUBG2
Summary
Paralog of TUBG1, required for centrosomal and noncentrosomal microtubule nucleation. Involved in specification of cell identity, such as stomatal patterning. Constitutively expressed throughout plant. Enriched at the post-cytokinetic cell edges in leaves and roots.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See GCP2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Sequence:
Chromosome: 5; NC_003076.8 (1679230..1682055)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene alfin-like 1 Neighboring gene Amino acid permease family protein Neighboring gene uncharacterized protein Neighboring gene nucleoprotein-like protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Cell edges accumulate gamma tubulin complex components and nucleate microtubules following cytokinesis in Arabidopsis thaliana. Ambrose C, et al. PLoS One, 2011. PMID 22110647, Free PMC Article
  2. Gamma-tubulin is essential for microtubule organization and development in Arabidopsis. Pastuglia M, et al. Plant Cell, 2006 Jun. PMID 16698945, Free PMC Article
  3. Gamma-tubulin is essential for acentrosomal microtubule nucleation and coordination of late mitotic events in Arabidopsis. Binarová P, et al. Plant Cell, 2006 May. PMID 16603653, Free PMC Article
  4. A mutation in the Arabidopsis gamma-tubulin-containing complex causes helical growth and abnormal microtubule branching. Nakamura M, et al. J Cell Sci, 2009 Jul 1. PMID 19509058
  5. Feeding cells induced by phytoparasitic nematodes require γ-tubulin ring complex for microtubule reorganization. Banora MY, et al. PLoS Pathog, 2011 Dec. PMID 22144887, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. gamma tubulin nucleation complex (GCP2 and GCP3) localize at distinct sites along the outer periclinal edge of newly formed crosswalls
    Title: Cell edges accumulate gamma tubulin complex components and nucleate microtubules following cytokinesis in Arabidopsis thaliana.
  2. Results show that a null mutation of Arabidopsis GCP2, a core subunit of the gamma-tubulin-containing complex, severely impaired the development of male and female gametophytes.
    Title: A mutation in the Arabidopsis gamma-tubulin-containing complex causes helical growth and abnormal microtubule branching.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_120644.3

Gene Ontology Provided by TAIR

Process Evidence Code Pubs
acts_upstream_of_or_within cellular localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cytokinesis by cell plate formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cytoplasmic microtubule organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within embryo sac development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within leaf development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within microtubule nucleation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within microtubule polymerization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within phragmoplast assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in response to nematode IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within root hair cell tip growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within stomatal complex morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of gamma-tubulin complex IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plant-type cell wall HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
gamma-tubulin complex protein 2
NP_196181.1
  • gamma-tubulin complex protein 2 (GCP2); FUNCTIONS IN: structural molecule activity, GTP binding, GTPase activity; INVOLVED IN: in 9 processes; LOCATED IN: in 6 components; CONTAINS InterPro DOMAIN/s: Gamma tubulin (InterPro:IPR002454), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: gamma-tubulin (TAIR:AT3G61650.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    1679230..1682055
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120644.3 → NP_196181.1  gamma-tubulin complex protein 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196181.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4IJ36, P38558
    UniProtKB/TrEMBL
    A0A178UJQ8, A0A5S9Y2E0, A0A7G2F8Q8
    Conserved Domains (1) summary
    PLN00222
    Location:1 → 454
    PLN00222; tubulin gamma chain; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38558.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools