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THO1 nuclear matrix protein-like protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830846, updated on 18-Sep-2024

Summary

Official Symbol
THO1
Official Full Name
nuclear matrix protein-like protein
Primary source
TAIR:AT5G09860
Locus tag
AT5G09860
See related
Araport:AT5G09860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtHPR1; AtTHO1; HPR1; MYH9.7; MYH9_7
Summary
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
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Genomic context

See THO1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
20
Sequence:
Chromosome: 5; NC_003076.8 (3066562..3070989)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Putative endonuclease or glycosyl hydrolase Neighboring gene Transcription elongation factor (TFIIS) family protein Neighboring gene cellulose synthase 5 Neighboring gene uncharacterized protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_001203340.2
NM_121023.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
part_of THO complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in intracellular anatomical structure IGI
Inferred from Genetic Interaction
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
nuclear matrix protein-like protein
NP_001190269.1
  • THO1; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: production of ta-siRNAs involved in RNA interference, gene silencing by RNA; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: THO complex, subunit THOC1 (InterPro:IPR021861).
NP_568219.1
  • THO1; CONTAINS InterPro DOMAIN/s: THO complex, subunit THOC1 (InterPro:IPR021861); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    3066562..3070989
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001203340.2NP_001190269.1  nuclear matrix protein-like protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UIV4, A0A7G2F9K6, F4KFC9
    Conserved Domains (1) summary
    pfam11957
    Location:87514
    efThoc1; THO complex subunit 1 transcription elongation factor
  2. NM_121023.4NP_568219.1  nuclear matrix protein-like protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8H134, Q93VM9, Q9FIC0
    UniProtKB/TrEMBL
    A0A178UJY8, A0A5S9Y2U1, A0A7G2F709
    Conserved Domains (1) summary
    pfam11957
    Location:87515
    efThoc1; THO complex subunit 1 transcription elongation factor