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Isocitrate/isopropylmalate dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831311, updated on 18-Sep-2024

Summary

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Official Full Name
Isocitrate/isopropylmalate dehydrogenase family protein
Primary source
TAIR:AT5G14590
Locus tag
AT5G14590
See related
Araport:AT5G14590
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T15N1.80; T15N1_80
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Genomic context

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Location:
chromosome: 5
Exon count:
15
Sequence:
Chromosome: 5; NC_003076.8 (4703298..4706826, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene high affinity nitrate transporter 2.7 Neighboring gene polyribonucleotide nucleotidyltransferase Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene methyltransferase-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Extra-Pathway Interactome of the TCA Cycle: Expected and Unexpected Metabolic Interactions. Zhang Y, et al. Plant Physiol, 2018 Jul. PMID 29794018, Free PMC Article
  2. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
  3. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
  4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
  5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_121463.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables isocitrate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in isocitrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma HDA PubMed 
located_in chloroplast thylakoid HDA PubMed 
located_in cytosol HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in plastid HDA PubMed 

General protein information

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Preferred Names
Isocitrate/isopropylmalate dehydrogenase family protein
NP_196963.2
  • Isocitrate/isopropylmalate dehydrogenase family protein; FUNCTIONS IN: NAD or NADH binding, isocitrate dehydrogenase (NADP+) activity, magnesium ion binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; INVOLVED IN: oxidation reduction, isocitrate metabolic process, metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate dehydrogenase NADP-dependent, eukaryotic (InterPro:IPR004790), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: cytosolic NADP+-dependent isocitrate dehydrogenase (TAIR:AT1G65930.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    4703298..4706826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121463.5 → NP_196963.2  Isocitrate/isopropylmalate dehydrogenase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196963.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LPJ5, Q9LYK1
    UniProtKB/TrEMBL
    A0A178UQB8, A0A5S9Y6C3, A0A654G163
    Conserved Domains (1) summary
    PLN03065
    Location:1 → 485
    PLN03065; isocitrate dehydrogenase (NADP+); Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8LPJ5.1

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