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DEL2 DP-E2F-like 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831348, updated on 18-Sep-2024

Summary

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Official Symbol
DEL2
Official Full Name
DP-E2F-like 2
Primary source
TAIR:AT5G14960
Locus tag
AT5G14960
See related
Araport:AT5G14960
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
DP-E2F-like 2; E2FD; E2L1; F2G14.80; F2G14_80
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Genomic context

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See DEL2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
11
Sequence:
Chromosome: 5; NC_003076.8 (4843855..4846664)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily protein Neighboring gene golgi alpha-mannosidase II Neighboring gene seed maturation-like protein Neighboring gene alpha/beta-Hydrolases superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The E2FD/DEL2 factor is a component of a regulatory network controlling cell proliferation and development in Arabidopsis. Sozzani R, et al. Plant Mol Biol, 2010 Mar. PMID 19937368
  2. The E2F family of transcription factors from Arabidopsis thaliana. Novel and conserved components of the retinoblastoma/E2F pathway in plants. Mariconti L, et al. J Biol Chem, 2002 Mar 22. PMID 11786543
  3. E2Ls, E2F-like repressors of Arabidopsis that bind to E2F sites in a monomeric form. Kosugi S, et al. J Biol Chem, 2002 May 10. PMID 11867638
  4. Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network. Boruc J, et al. Plant Cell, 2010 Apr. PMID 20407024, Free PMC Article
  5. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Efroni I, et al. Dev Cell, 2013 Feb 25. PMID 23449474, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. E2FD/DEL2 accumulation is subject to negative post-translational regulation mediated by the plant hormone auxin.
    Title: The E2FD/DEL2 factor is a component of a regulatory network controlling cell proliferation and development in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in response to auxin IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DP-E2F-like 2
NP_197000.1
  • DP-E2F-like 2 (DEL2); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Transcription factor E2F/dimerisation partner (TDP) (InterPro:IPR003316), E2F Family (InterPro:IPR015633); BEST Arabidopsis thaliana protein match is: DP-E2F-like protein 3 (TAIR:AT3G01330.1); Has 936 Blast hits to 860 proteins in 115 species: Archae - 0; Bacteria - 0; Metazoa - 583; Fungi - 5; Plants - 220; Viruses - 0; Other Eukaryotes - 128 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    4843855..4846664
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121500.4 → NP_197000.1  DP-E2F-like 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197000.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LFQ9
    UniProtKB/TrEMBL
    A0A178UM45, A0A5S9Y4I7
    Conserved Domains (1) summary
    pfam02319
    Location:15 → 78
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  2. NM_001343379.1 → NP_001330250.1  DP-E2F-like 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BA83
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LFQ9.1

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