U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

UGD3 UDP-glucose 6-dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831402, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
UGD3
Official Full Name
UDP-glucose 6-dehydrogenase family protein
Primary source
TAIR:AT5G15490
Locus tag
AT5G15490
See related
Araport:AT5G15490
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T20K14.100; T20K14_100; UDP-glucose dehydrogenase 3
Summary
Encodes one of four UDP-glucose dehydrogenase UGD) genes. Mutation of this gene in combination with UGD2 leads to swollen plant cell walls and severe developmental defects associated with changes in pectic polysaccharides.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See UGD3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (5027638..5030245, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene galacturonosyltransferase 14 Neighboring gene C2H2-type zinc finger family protein Neighboring gene Ankyrin repeat family protein Neighboring gene TPX2 (targeting protein for Xklp2) protein family

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Down-regulation of UDP-glucuronic acid biosynthesis leads to swollen plant cell walls and severe developmental defects associated with changes in pectic polysaccharides. Reboul R, et al. J Biol Chem, 2011 Nov 18. PMID 21949134, Free PMC Article
  2. Genome-wide analysis of the UDP-glucose dehydrogenase gene family in Arabidopsis, a key enzyme for matrix polysaccharides in cell walls. Klinghammer M, et al. J Exp Bot, 2007. PMID 18057039
  3. The 14-3-3 isoforms chi and epsilon differentially bind client proteins from developing Arabidopsis seed. Swatek KN, et al. J Proteome Res, 2011 Sep 2. PMID 21766784
  4. Arabidopsis cell wall proteome defined using multidimensional protein identification technology. Bayer EM, et al. Proteomics, 2006 Jan. PMID 16287169
  5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_121553.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables UDP-glucose 6-dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables UDP-glucose 6-dehydrogenase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in UDP-glucuronate biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in UDP-glucuronate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within carbohydrate metabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within cell wall pectin metabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in plant-type cell wall HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
UDP-glucose 6-dehydrogenase family protein
NP_197053.1
  • UDP-glucose 6-dehydrogenase family protein; FUNCTIONS IN: in 7 functions; INVOLVED IN: oxidation reduction, metabolic process; LOCATED IN: cytosol, cell wall, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: UDP-glucose/GDP-mannose dehydrogenase, N-terminal (InterPro:IPR001732), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), UDP-glucose/GDP-mannose dehydrogenase, dimerisation and substrate-binding domain (InterPro:IPR014028), UDP-glucose/GDP-mannose dehydrogenase, C-terminal (InterPro:IPR014027), NAD(P)-binding domain (InterPro:IPR016040), UDP-glucose/GDP-mannose dehydrogenase, dimerisation (InterPro:IPR014026), Nucleotide sugar dehydrogenase (InterPro:IPR017476); BEST Arabidopsis thaliana protein match is: UDP-glucose 6-dehydrogenase family protein (TAIR:AT3G29360.2); Has 13373 Blast hits to 13344 proteins in 2170 species: Archae - 309; Bacteria - 7111; Metazoa - 214; Fungi - 99; Plants - 213; Viruses - 14; Other Eukaryotes - 5413 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    5027638..5030245 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121553.4 → NP_197053.1  UDP-glucose 6-dehydrogenase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197053.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LF33
    UniProtKB/TrEMBL
    A0A178UJW9, A0A178VPC3, A0A5S9XH23, A0A5S9Y4C2
    Conserved Domains (1) summary
    PLN02353
    Location:1 → 473
    PLN02353; probable UDP-glucose 6-dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LF33.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools