COL1 CONSTANS-like 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: COL1
Official Full Name: CONSTANS-like 1
Primary source: TAIR:AT5G15850
Locus tag: AT5G15850
See related: Araport:AT5G15850
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATCOL1; B-box domain protein 2; BBX2; CONSTANS-like 1; F14F8.230; F14F8_230
Summary: Homologous to the flowering-time gene CONSTANS.
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Genomic context

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See COL1 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 2

Sequence:: Chromosome: 5; NC_003076.8 (5176091..5177897, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MED25 links COI1 with HAC1-dependent H3K9 acetylation to activate MYC2-regulated transcription of jasmonic acid-responsive genes.COI1 Is enriched on the promoters of JAZ8 and ERF1.
Title: Mediator subunit MED25 links the jasmonate receptor to transcriptionally active chromatin.
The lack of flowering promotion activity by COL1 and COL2 is mainly attributed to the differences between CO and the COL1 and COL2 proteins in the amino acid sequence encoded by their first exons.
Title: The sequence variation responsible for the functional difference between the CONSTANS protein, and the CONSTANS-like (COL) 1 and COL2 proteins, resides mostly in the region encoded by their first exons.
our data demonstrate a role for COI1 in disease resistance independent of Jasmonic Acid signaling and provide a molecular link between the JA and NB-LRR signaling pathways.
Title: Specific missense alleles of the arabidopsis jasmonic acid co-receptor COI1 regulate innate immune receptor accumulation and function.
Both COL1 and COR27 were found to be regulated by the circadian clock at warm growth temperatures.
Title: A role for circadian evening elements in cold-regulated gene expression in Arabidopsis.
The data demonstrate that ax6 enhances the effect of coi1 on JA responses, implying a genetic interaction between COI1 and AtCUL1 in JA signaling.
Title: Point mutations in Arabidopsis Cullin1 reveal its essential role in jasmonate response.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_121590.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within circadian rhythm	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of flower development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: CONSTANS-like 1

NP_197089.1

CONSTANS-like 1 (COL1); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity, zinc ion binding; INVOLVED IN: circadian rhythm, regulation of flower development; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: CCT domain (InterPro:IPR010402), Zinc finger, B-box (InterPro:IPR000315); BEST Arabidopsis thaliana protein match is: B-box type zinc finger protein with CCT domain (TAIR:AT5G15840.1); Has 3200 Blast hits to 2506 proteins in 141 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 0; Plants - 3006; Viruses - 0; Other Eukaryotes - 193 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

5176091..5177897 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_121590.2 → NP_197089.1 CONSTANS-like 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_197089.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O50055

UniProtKB/TrEMBL

A0A178U9N1, A0A5S9Y4H5, A0A654G1J6

Conserved Domains (2) summary

cd19821
Location:11 → 54

Bbox1_BBX-like; B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins

pfam06203
Location:286 → 329

CCT; CCT motif