U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RAD4 DNA repair protein Rad4 family [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831525, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
RAD4
Official Full Name
DNA repair protein Rad4 family
Primary source
TAIR:AT5G16630
Locus tag
AT5G16630
See related
Araport:AT5G16630
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATRAD4; MTG13.7; MTG13_7
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See RAD4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
12
Sequence:
Chromosome: 5; NC_003076.8 (5454654..5459647)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene miscRNA Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. CENTRIN2 interacts with the Arabidopsis homolog of the human XPC protein (AtRAD4) and contributes to efficient synthesis-dependent repair of bulky DNA lesions. Liang L, et al. Plant Mol Biol, 2006 May. PMID 16786311
  2. RAD4 and RAD23/HMR Contribute to Arabidopsis UV Tolerance. Lahari T, et al. Genes (Basel), 2017 Dec 28. PMID 29283431, Free PMC Article
  3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
  4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RAD4 interacts with the distal EF-hand Ca(2+) binding domain of CEN2 and this interaction is required for efficient nucleotide excision repair. [RAD4]
    Title: CENTRIN2 interacts with the Arabidopsis homolog of the human XPC protein (AtRAD4) and contributes to efficient synthesis-dependent repair of bulky DNA lesions.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_001036817.3
NM_121669.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in UV protection IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within_positive_effect double-strand break repair via homologous recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within_positive_effect nucleotide-excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within_positive_effect response to UV IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
DNA repair protein Rad4 family
NP_001031894.1
  • RAD4; FUNCTIONS IN: damaged DNA binding; INVOLVED IN: nucleotide-excision repair; LOCATED IN: nucleus, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Transglutaminase-like (InterPro:IPR002931), DNA repair protein Rad4, DNA-binding domain 1 (InterPro:IPR018326), DNA repair protein Rad4, DNA-binding domain 3 (InterPro:IPR018328), DNA repair protein Rad4, DNA-binding domain 2 (InterPro:IPR018327), DNA repair protein Rad4, transglutaminase-like domain (InterPro:IPR018325), DNA repair protein Rad4 (InterPro:IPR004583); Has 662 Blast hits to 576 proteins in 184 species: Archae - 0; Bacteria - 0; Metazoa - 224; Fungi - 265; Plants - 79; Viruses - 0; Other Eukaryotes - 94 (source: NCBI BLink).
NP_197166.2
  • RAD4; FUNCTIONS IN: damaged DNA binding; INVOLVED IN: nucleotide-excision repair; LOCATED IN: nucleus, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Transglutaminase-like (InterPro:IPR002931), DNA repair protein Rad4, DNA-binding domain 1 (InterPro:IPR018326), DNA repair protein Rad4, DNA-binding domain 3 (InterPro:IPR018328), DNA repair protein Rad4, DNA-binding domain 2 (InterPro:IPR018327), DNA repair protein Rad4, transglutaminase-like domain (InterPro:IPR018325), DNA repair protein Rad4 (InterPro:IPR004583); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    5454654..5459647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001343458.1 → NP_001332636.1  DNA repair protein Rad4 family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1R7T387
    Conserved Domains (1) summary
    TIGR00605
    Location:107 → 618
    rad4; DNA repair protein rad4

  2. NM_001036817.3 → NP_001031894.1  DNA repair protein Rad4 family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031894.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8W489
    UniProtKB/TrEMBL
    A0A178UQJ6, A0A5S9Y4Q4
    Conserved Domains (1) summary
    TIGR00605
    Location:107 → 781
    rad4; DNA repair protein rad4

  3. NM_121669.3 → NP_197166.2  DNA repair protein Rad4 family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197166.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8W489
    UniProtKB/TrEMBL
    A0A178UQJ6, A0A5S9Y4Q4
    Conserved Domains (1) summary
    TIGR00605
    Location:107 → 781
    rad4; DNA repair protein rad4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8W489.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools