DHAR3 dehydroascorbate reductase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: DHAR3
Official Full Name: dehydroascorbate reductase 1
Primary source: TAIR:AT5G16710
Locus tag: AT5G16710
See related: Araport:AT5G16710
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: dehydroascorbate reductase 1; F5E19.50; F5E19_50
Summary: The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide.
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_121676.4

Function	Evidence Code	Pubs
enables glutathione dehydrogenase (ascorbate) activity	IDA Inferred from Direct Assay more info	PubMed
enables glutathione dehydrogenase (ascorbate) activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables glutathione transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within L-ascorbic acid metabolic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within acquisition of seed longevity	IGI Inferred from Genetic Interaction more info	PubMed
involved_in ascorbate glutathione cycle	IEA Inferred from Electronic Annotation more info
involved_in cellular oxidant detoxification	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cellular oxidant detoxification	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein glutathionylation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast envelope	HDA more info	PubMed
located_in chloroplast stroma	HDA more info	PubMed
located_in plastid	HDA more info	PubMed

NP_568336.1

dehydroascorbate reductase 1 (DHAR3); FUNCTIONS IN: glutathione dehydrogenase (ascorbate) activity; INVOLVED IN: protein amino acid glutathionylation; LOCATED IN: chloroplast stroma, chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Glutathione S-transferase, C-terminal-like (InterPro:IPR010987), Glutathione S-transferase/chloride channel, C-terminal (InterPro:IPR017933), Glutathione S-transferase, N-terminal (InterPro:IPR004045), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: dehydroascorbate reductase 2 (TAIR:AT1G75270.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).