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kinase family with ARM repeat domain-containing protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831988, updated on 18-Sep-2024

Summary

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Official Full Name
kinase family with ARM repeat domain-containing protein
Primary source
TAIR:AT5G18700
Locus tag
AT5G18700
See related
Araport:AT5G18700
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
EMB3013; EMBRYO DEFECTIVE 3013; RUK; RUNKEL; T1A4.80; T1A4_80
Summary
Encodes a microtubule-associated kinase-like protein RUNKEL (RUK). Contains a putative serine/threonine kinase domain and a microtubule-binding domain. RUK directly binds to microtubules in vitro and colocalizes with mitotic preprophase band, spindle, and phragmoplast in vivo. Required for cell plate expansion in cytokinesis.
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Genomic context

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Location:
chromosome: 5
Exon count:
11
Sequence:
Chromosome: 5; NC_003076.8 (6235032..6240916, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene beta-amylase 3 Neighboring gene tubby like protein 11 Neighboring gene arabinogalactan protein 25 Neighboring gene uncharacterized protein Neighboring gene DNAJ heat shock amino-terminal domain protein, putative (DUF3444) Neighboring gene DNAJ heat shock amino-terminal domain protein, putative (DUF3444)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Microtubule-associated kinase-like protein RUNKEL needed [corrected] for cell plate expansion in Arabidopsis cytokinesis. Krupnova T, et al. Curr Biol, 2009 Mar 24. PMID 19268593
  2. Cellularisation in the endosperm of Arabidopsis thaliana is coupled to mitosis and shares multiple components with cytokinesis. Sørensen MB, et al. Development, 2002 Dec. PMID 12421698
  3. Genetic dissection of cytokinesis. Nacry P, et al. Plant Mol Biol, 2000 Aug. PMID 11089872
  4. The microtubule-associated kinase-like protein RUNKEL functions in somatic and syncytial cytokinesis. Krupnova T, et al. Plant J, 2013 Jun. PMID 23451828
  5. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data indicate a role for RUNKEL (RUK) in both phragmoplast-based cytokinesis in somatic cells and syncytial cytokinesis in reproductive cells.
    Title: The microtubule-associated kinase-like protein RUNKEL functions in somatic and syncytial cytokinesis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_121875.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
NOT enables kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables microtubule binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellularization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cytokinesis by cell plate formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within embryo development ending in seed dormancy NAS
Non-traceable Author Statement
more info
  
acts_upstream_of_or_within endosperm cellularization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endosperm cellularization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in microsporogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within phragmoplast assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pollen development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in radial microtubular system formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
colocalizes_with microtubule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in phragmoplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  
located_in plasmodesma HDA PubMed 
located_in preprophase band IDA
Inferred from Direct Assay
more info
 PubMed 
located_in spindle IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
kinase family with ARM repeat domain-containing protein
NP_197371.2
  • Protein kinase family protein with ARM repeat domain; CONTAINS InterPro DOMAIN/s: Serine/threonine-protein kinase domain (InterPro:IPR002290), Armadillo-like helical (InterPro:IPR011989), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G33940.2); Has 133671 Blast hits to 131461 proteins in 4761 species: Archae - 230; Bacteria - 15366; Metazoa - 49337; Fungi - 13216; Plants - 32681; Viruses - 728; Other Eukaryotes - 22113 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    6235032..6240916 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121875.4 → NP_197371.2  kinase family with ARM repeat domain-containing protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197371.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4JY37
    UniProtKB/TrEMBL
    A0A178UQV6, A0A5S9Y5B7, A0A654G2D7
    Conserved Domains (1) summary
    cd14010
    Location:3 → 253
    STKc_ULK4; Catalytic domain of the Serine/Threonine kinase, Unc-51-like kinase 4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4JY37.1

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