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Protein phosphatase 2C family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832860, updated on 18-Sep-2024

Summary

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Official Full Name
Protein phosphatase 2C family protein
Primary source
TAIR:AT5G27930
Locus tag
AT5G27930
See related
Araport:AT5G27930
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F15F15.3
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Genomic context

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Location:
chromosome: 5
Exon count:
6
Sequence:
Chromosome: 5; NC_003076.8 (9957816..9961374, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EGR2 phosphatase regulates OST1 kinase activity and freezing tolerance in Arabidopsis. Ding Y, et al. EMBO J, 2019 Jan 3. PMID 30429206, Free PMC Article
  2. Spatial differences in stoichiometry of EGR phosphatase and Microtubule-associated Stress Protein 1 control root meristem activity during drought stress. Longkumer T, et al. Plant Cell, 2022 Feb 3. PMID 34865106, Free PMC Article
  3. Protein Phosphatase 2Cs and Microtubule-Associated Stress Protein 1 Control Microtubule Stability, Plant Growth, and Drought Response. Bhaskara GB, et al. Plant Cell, 2017 Jan. PMID 28011693, Free PMC Article
  4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Spatial differences in stoichiometry of EGR phosphatase and Microtubule-associated Stress Protein 1 control root meristem activity during drought stress.
    Title: Spatial differences in stoichiometry of EGR phosphatase and Microtubule-associated Stress Protein 1 control root meristem activity during drought stress.
  2. A molecular mechanism underlying cold activation of OST1 by membrane-localized EGR2 and this suggests a myristoyl switch on EGR2 helps plants to adapt to cold stress.
    Title: EGR2 phosphatase regulates OST1 kinase activity and freezing tolerance in Arabidopsis.
  3. The EGR (clade E growth-regulating (EGR) type 2C protein phosphatases)-MASP1 (microtubule-associated stress protein 1 (MASP1; AT4G03260) system selectively regulates microtubule recovery and stability to adjust plant growth and cell expansion in response to changing environmental conditions.
    Title: Protein Phosphatase 2Cs and Microtubule-Associated Stress Protein 1 Control Microtubule Stability, Plant Growth, and Drought Response.
Submit: New GeneRIF Correction

General gene information

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NM_001344046.1
NM_122675.4
NM_180755.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within drought recovery IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within microtubule cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within negative regulation of growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein dephosphorylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Protein phosphatase 2C family protein
NP_568503.1
  • Protein phosphatase 2C family protein; FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT3G05640.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_851086.1
  • Protein phosphatase 2C family protein; FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT3G05640.2); Has 5854 Blast hits to 5851 proteins in 292 species: Archae - 2; Bacteria - 6; Metazoa - 1439; Fungi - 687; Plants - 2519; Viruses - 5; Other Eukaryotes - 1196 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    9957816..9961374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_122675.4 → NP_568503.1  Protein phosphatase 2C family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568503.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WM64, Q0WRB2, Q8GX49, Q8LD08, Q8SBC4
    UniProtKB/TrEMBL
    A0A7G2FD10
    Conserved Domains (1) summary
    cd00143
    Location:62 → 353
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

  2. NM_001344046.1 → NP_001332736.1  Protein phosphatase 2C family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1R7T3I5, A0A7G2FD10
    Conserved Domains (1) summary
    cd00143
    Location:62 → 301
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

  3. NM_180755.2 → NP_851086.1  Protein phosphatase 2C family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_851086.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WM64, Q0WRB2, Q8GX49, Q8LD08, Q8SBC4
    UniProtKB/TrEMBL
    A0A7G2FD10
    Conserved Domains (1) summary
    cd00143
    Location:62 → 353
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0WRB2.1

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