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ANX2 Malectin/receptor-like protein kinase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832975, updated on 18-Sep-2024

Summary

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Official Symbol
ANX2
Official Full Name
Malectin/receptor-like protein kinase family protein
Primary source
TAIR:AT5G28680
Locus tag
AT5G28680
See related
Araport:AT5G28680
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ANXUR2; F4I4.60; F4I4_60
Summary
Receptor-like kinase required for maintenance of pollen tube growth. Display polar localization at the plasma membrane of the pollen tube tip.
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Genomic context

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See ANX2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (10719127..10722361, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene carboxylate clamp-TPR protein (DUF1685) Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structures of the extracellular domains of the CrRLK1L receptor-like kinases ANXUR1 and ANXUR2. Du S, et al. Protein Sci, 2018 Apr. PMID 29388293, Free PMC Article
  2. Differential Regulation of Two-Tiered Plant Immunity and Sexual Reproduction by ANXUR Receptor-Like Kinases. Mang H, et al. Plant Cell, 2017 Dec. PMID 29150546, Free PMC Article
  3. T-DNA-induced chromosomal translocations in feronia and anxur2 mutants reveal implications for the mechanism of collapsed pollen due to chromosomal rearrangements. Ruprecht C, et al. Mol Plant, 2014 Oct. PMID 24874868
  4. ANXUR1 and 2, sister genes to FERONIA/SIRENE, are male factors for coordinated fertilization. Miyazaki S, et al. Curr Biol, 2009 Aug 11. PMID 19646876
  5. Disruption of the pollen-expressed FERONIA homologs ANXUR1 and ANXUR2 triggers pollen tube discharge. Boisson-Dernier A, et al. Development, 2009 Oct. PMID 19736323, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. uncoupled functions of ANX1 and ANX2 during plant immunity and sexual reproduction, are reported.
    Title: Differential Regulation of Two-Tiered Plant Immunity and Sexual Reproduction by ANXUR Receptor-Like Kinases.
  2. Crystal structure shows that ANX2 extracellular domain lack residues involved in binding to the diglucosides.
    Title: Crystal structures of the extracellular domains of the CrRLK1L receptor-like kinases ANXUR1 and ANXUR2.
  3. Three independent T-DNA insertion lines for FERONIA and its pollen-specific homolog ANXUR2 showing deformed pollen phenotypes caused by chromosomal translocations, were identified.
    Title: T-DNA-induced chromosomal translocations in feronia and anxur2 mutants reveal implications for the mechanism of collapsed pollen due to chromosomal rearrangements.
  4. study reports that pollen tubes of anx1/anx2 mutants ruptured before arriving at the egg apparatus, suggesting that ANX1(At3g04690) and ANX2(At5g28680)are male factors controlling pollen tube behavior by directing rupture at proper timing
    Title: ANXUR1 and 2, sister genes to FERONIA/SIRENE, are male factors for coordinated fertilization.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001344080.1
NM_122751.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within pollen tube growth IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in pollen tube tip IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Malectin/receptor-like protein kinase family protein
NP_001318669.1
  • ANXUR2 (ANX2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: pollen tube growth; LOCATED IN: apical plasma membrane; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Malectin/receptor-like protein kinase (InterPro:IPR021720), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Malectin/receptor-like protein kinase family protein (TAIR:AT3G04690.1); Has 115671 Blast hits to 114295 proteins in 4417 species: Archae - 97; Bacteria - 12752; Metazoa - 43268; Fungi - 9644; Plants - 32773; Viruses - 427; Other Eukaryotes - 16710 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    10719127..10722361 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001344080.1 → NP_001318669.1  Malectin/receptor-like protein kinase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3E8W4
    UniProtKB/TrEMBL
    A0A654G521
    Conserved Domains (4) summary
    smart00221
    Location:526 → 788
    STYKc; Protein kinase; unclassified specificity
    cd14066
    Location:527 → 792
    STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    pfam11721
    Location:213 → 367
    Malectin; Di-glucose binding within endoplasmic reticulum
    pfam12819
    Location:32 → 399
    Malectin_like; Carbohydrate-binding protein of the ER

  2. NM_122751.2 → NP_198220.1  Malectin/receptor-like protein kinase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198220.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3E8W4
    UniProtKB/TrEMBL
    A0A654G521
    Conserved Domains (4) summary
    smart00221
    Location:526 → 788
    STYKc; Protein kinase; unclassified specificity
    cd14066
    Location:527 → 792
    STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    pfam11721
    Location:213 → 367
    Malectin; Di-glucose binding within endoplasmic reticulum
    pfam12819
    Location:32 → 399
    Malectin_like; Carbohydrate-binding protein of the ER
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3E8W4.1

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