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Protein with RING/U-box and TRAF-like domain [ Arabidopsis thaliana (thale cress) ]

Gene ID: 833768, updated on 18-Sep-2024

Summary

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Official Full Name
Protein with RING/U-box and TRAF-like domain
Primary source
TAIR:AT5G37890
Locus tag
AT5G37890
See related
Araport:AT5G37890
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtSINAL7; K18L3.9; K18L3_9; SINA like 7; SINAL7
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Genomic context

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Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (15089678..15091955, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene TRAF-like superfamily protein Neighboring gene Protein with RING/U-box and TRAF-like domain

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Over-expression of SINAL7 increases biomass and drought tolerance, and also delays senescence in Arabidopsis. Peralta DA, et al. J Biotechnol, 2018 Oct 10. PMID 30003973
  2. Characterization of the Arabidopsis thaliana E3 ubiquitin-ligase AtSINAL7 and identification of the ubiquitination sites. Peralta DA, et al. PLoS One, 2013. PMID 24015288, Free PMC Article
  3. The E3 ubiquitin-ligase SEVEN IN ABSENTIA like 7 mono-ubiquitinates glyceraldehyde-3-phosphate dehydrogenase 1 isoform in vitro and is required for its nuclear localization in Arabidopsis thaliana. Peralta DA, et al. Int J Biochem Cell Biol, 2016 Jan. PMID 26582368
  4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Study showed that SINAL7 over-expression had a positive effect on vegetative growth in Arabidopsis, resulting in sucrose and hexose levels increase and leading to a higher biomass content associated with stomatal closure and drought tolerance. The SINAL7-over-expressing plants showed a delay in senescence, with no signs of aging at the transcriptional level and in terms of chlorophyll content or leaf yellowing.
    Title: Over-expression of SINAL7 increases biomass and drought tolerance, and also delays senescence in Arabidopsis.
  2. Data suggests a role for SINAL7 in the regulation of both, the activity and the localization of GAPC1 that could be relevant to the physiology of plant cells. [SINAl7]
    Title: The E3 ubiquitin-ligase SEVEN IN ABSENTIA like 7 mono-ubiquitinates glyceraldehyde-3-phosphate dehydrogenase 1 isoform in vitro and is required for its nuclear localization in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_123148.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein ubiquitination IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to UV IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Protein with RING/U-box and TRAF-like domain
NP_198605.2
  • Protein with RING/U-box and TRAF-like domains; FUNCTIONS IN: ubiquitin-protein ligase activity, zinc ion binding; INVOLVED IN: multicellular organismal development, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: nucleus, intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), TRAF-like (InterPro:IPR008974), Seven-in-absentia protein, TRAF-like domain (InterPro:IPR018121), Zinc finger, SIAH-type (InterPro:IPR013010), Zinc finger, RING-type (InterPro:IPR001841), Seven In Absentia Homolog-type (InterPro:IPR013323), Seven-in-absentia protein, sina (InterPro:IPR004162); BEST Arabidopsis thaliana protein match is: Protein with RING/U-box and TRAF-like domains (TAIR:AT5G37910.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    15089678..15091955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123148.4 → NP_198605.2  Protein with RING/U-box and TRAF-like domain [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198605.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FKD7
    UniProtKB/TrEMBL
    A0A178UNQ6, A0A654G6T5
    Conserved Domains (2) summary
    cd16571
    Location:49 → 86
    RING-HC_SIAHs; RING finger, HC subclass, found in Drosophila melanogaster protein Seven-in-Absentia (sina) and its homologs
    cl19105
    Location:94 → 164
    Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FKD7.1

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