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BEL1 POX (plant homeobox) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834143, updated on 18-Sep-2024

Summary

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Official Symbol
BEL1
Official Full Name
POX (plant homeobox) family protein
Primary source
TAIR:AT5G41410
Locus tag
AT5G41410
See related
Araport:AT5G41410
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
BELL 1; MYC6.12; MYC6_12
Summary
Homeodomain protein required for ovule identity.Loss of function mutations show homeotic conversion of integuments to carpels.Forms heterodimers with STM and KNAT1. Interacts with AG-SEP heterodimers is thought to restrict WUS expression. BEL interacts with MADS box dimers composed of SEP1(or SEP3) and AG, SHP1, SHP2 and STK. The interaction of BEL1 with AG-SEP3 is required for proper integument development and specification of integument identity.
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Genomic context

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See BEL1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (16579936..16584077)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene RING/U-box superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Homeotic Transformation of Ovules into Carpel-like Structures in Arabidopsis. Modrusan Z, et al. Plant Cell, 1994 Mar. PMID 12244239, Free PMC Article
  2. The BELL1 gene encodes a homeodomain protein involved in pattern formation in the Arabidopsis ovule primordium. Reiser L, et al. Cell, 1995 Dec 1. PMID 8521490
  3. The transcription factors BEL1 and SPL are required for cytokinin and auxin signaling during ovule development in Arabidopsis. Bencivenga S, et al. Plant Cell, 2012 Jul. PMID 22786869, Free PMC Article
  4. CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules. Yamada T, et al. Development, 2016 Feb 1. PMID 26700684
  5. The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals. Bellaoui M, et al. Plant Cell, 2001 Nov. PMID 11701881, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The branching ovules of the mutant resemble those of some fossil gymnosperms, implicating BEL1 and HD-ZIPIII genes as players in the evolution of the unbranched ovule form in extant angiosperms.
    Title: CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules.
  2. The transcription factors BEL1 and SPL/NZZ, previously described as key regulators of ovule development, are needed for the auxin and cytokinin signaling pathways for the correct patterning of the ovule.
    Title: The transcription factors BEL1 and SPL are required for cytokinin and auxin signaling during ovule development in Arabidopsis.
  3. BEL1 interacts with the ovule identity MADS box factors when they dimerize with SEPALLATA proteins.
    Title: Genetic and molecular interactions between BELL1 and MADS box factors support ovule development in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_123506.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within plant ovule development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plasmodesma HDA PubMed 

General protein information

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Preferred Names
POX (plant homeobox) family protein
NP_198957.1
  • BELL 1 (BEL1); CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), POX (InterPro:IPR006563), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: BEL1-like homeodomain 4 (TAIR:AT2G23760.3); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    16579936..16584077
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123506.3 → NP_198957.1  POX (plant homeobox) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198957.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q38897, Q93Y33, Q9FN59
    UniProtKB/TrEMBL
    A0A178U8G7, A0A5S9Y9W2
    Conserved Domains (2) summary
    smart00574
    Location:192 → 338
    POX; domain associated with HOX domains
    pfam05920
    Location:409 → 448
    Homeobox_KN; Homeobox KN domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q38897.2

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