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Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834556, updated on 18-Sep-2024

Summary

Official Full Name
Disease resistance protein (TIR-NBS-LRR class) family
Primary source
TAIR:AT5G45200
Locus tag
AT5G45200
See related
Araport:AT5G45200
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
K18C1.8; K18C1_8
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Genomic context

Location:
chromosome: 5
Exon count:
5
Sequence:
Chromosome: 5; NC_003076.8 (18283663..18290478, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Flavin-binding monooxygenase family protein Neighboring gene Cyclin family protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family

General gene information

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
Disease resistance protein (TIR-NBS-LRR class) family
NP_199333.1
  • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat, typical subtype (InterPro:IPR003591), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT4G36150.1); Has 28903 Blast hits to 18982 proteins in 765 species: Archae - 18; Bacteria - 1854; Metazoa - 4567; Fungi - 301; Plants - 21032; Viruses - 0; Other Eukaryotes - 1131 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    18283663..18290478 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123888.2NP_199333.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_199333.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2FIC3, F4KD45
    Conserved Domains (6) summary
    cd09293
    Location:637788
    AMN1; Antagonist of mitotic exit network protein 1
    COG4886
    Location:639861
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:641663
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00931
    Location:218472
    NB-ARC; NB-ARC domain
    pfam01582
    Location:19179
    TIR; TIR domain
    cl21455
    Location:221361
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. NM_001344596.1NP_001332396.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BGV5, A0A7G2FIC3
  3. NM_001344597.1NP_001332395.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BGV4