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IMPA-8 importin alpha isoform 8 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835275, updated on 18-Sep-2024

Summary

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Official Symbol
IMPA-8
Official Full Name
importin alpha isoform 8
Primary source
TAIR:AT5G52000
Locus tag
AT5G52000
See related
Araport:AT5G52000
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
importin alpha isoform 8; MSG15.24; MSG15_24
Summary
Putative importin alpha isoform. When overexpressed can rescue the impa-4 decreased transformation susceptibility phenotype. Target promoter of the male germline-specific transcription factor DUO1.
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Genomic context

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See IMPA-8 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Sequence:
Chromosome: 5; NC_003076.8 (21118946..21121119, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene GroES-like zinc-binding alcohol dehydrogenase family protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene C-repeat-binding factor 4 Neighboring gene C2H2-like zinc finger protein Neighboring gene Integrase-type DNA-binding superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The R2R3 MYB transcription factor DUO1 activates a male germline-specific regulon essential for sperm cell differentiation in Arabidopsis. Borg M, et al. Plant Cell, 2011 Feb. PMID 21285328, Free PMC Article
  2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables nuclear import signal receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within pollen sperm cell differentiation IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in protein import into nucleus IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
importin alpha isoform 8
NP_200013.1
  • importin alpha isoform 8 (IMPA-8); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport; LOCATED IN: cellular_component unknown; EXPRESSED IN: sperm cell, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), HEAT, type 2 (InterPro:IPR021133), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: importin alpha isoform 1 (TAIR:AT3G06720.2); Has 3277 Blast hits to 2522 proteins in 278 species: Archae - 2; Bacteria - 4; Metazoa - 1316; Fungi - 608; Plants - 711; Viruses - 0; Other Eukaryotes - 636 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    21118946..21121119 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_124579.2 → NP_200013.1  importin alpha isoform 8 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_200013.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FJ92
    UniProtKB/TrEMBL
    A0A5S9YD78
    Conserved Domains (5) summary
    cd00020
    Location:171 → 284
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam13646
    Location:51 → 156
    HEAT_2; HEAT repeats
    pfam16186
    Location:382 → 421
    Arm_3; Atypical Arm repeat
    sd00044
    Location:14 → 39
    HEAT; HEAT repeat [structural motif]
    sd00043
    Location:172 → 197
    ARM; armadillo repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FJ92.1

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