XYLT beta-1,2-xylosyltransferase [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: XYLT
Official Full Name: beta-1,2-xylosyltransferase
Primary source: TAIR:AT5G55500
Locus tag: AT5G55500
See related: Araport:AT5G55500
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ''beta-1; 2-xylosyltransferase; 2-XYLOSYLTRANSFERASE; 2-xylosyltransferase''; ARABIDOPSIS THALIANA BETA-1; ATXYLT; beta-1
Summary: Encodes a beta-1,2-xylosyltransferase that is glycosylated at two positions.
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Genomic context

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See XYLT in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 3

Sequence:: Chromosome: 5; NC_003076.8 (22482125..22484631)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AtXYLT acts on protein-bound N-glycans prior to alpha1,3-fucosyltransferase and mannosidase II.
Title: Arabidopsis β1,2-xylosyltransferase: substrate specificity and participation in the plant-specific N-glycosylation pathway.
The substrate specificity of XylT permits the enzyme to act at multiple stages of the plant N-glycosylation pathway.
Title: Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway.
Data show that expression of a hybrid enzyme of Arabidopsis thaliana xylosyltransferase and human beta-1,4-galactosyltransferase I in tobacco causes a reduction of N-glycans with potentially immunogenic core-bound xylose and fucose residues.
Title: An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_124932.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables glycoprotein 2-beta-D-xylosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables xylosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within post-translational protein targeting to membrane, translocation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within protein N-linked glycosylation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	HDA more info	PubMed
located_in Golgi medial cisterna	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi membrane	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in Golgi trans cisterna	HDA more info	PubMed
located_in extracellular region	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: beta-1,2-xylosyltransferase

NP_568825.1

''beta-1,2-xylosyltransferase'' (XYLT); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

22482125..22484631

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_124932.4 → NP_568825.1 beta-1,2-xylosyltransferase [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_568825.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LDH0, Q9LKK7

UniProtKB/TrEMBL

A0A5S9YFE5, W8PUA9

Conserved Domains (1) summary

pfam04577
Location:248 → 513

DUF563; Protein of unknown function (DUF563)