NDL1 N-MYC downregulated-like 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: NDL1
Official Full Name: N-MYC downregulated-like 1
Primary source: TAIR:AT5G56750
Locus tag: AT5G56750
See related: Araport:AT5G56750
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MIK19.22; MIK19_22; N-MYC downregulated-like 1
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Genomic context

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See NDL1 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 11

Sequence:: Chromosome: 5; NC_003076.8 (22957629..22960916)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results from translational fusion of AtNDL1 and AtRAD5B in seedlings and reproductive organs revealed that both shared similar expression patterns with the highest expression observed in male reproductive organs. Moreover, they shared similar domains of localization in roots, suggesting their potential functioning together in reproductive and root development processes.
Title: Comparative expression profiling of AtRAD5B and AtNDL1: Hints towards a role in G protein mediated signaling.
AGB1 and NDL1 positively regulate basipetal inflorescence auxin transport and modulate MAX2 expression in shoots.
Title: N-MYC down-regulated-like proteins regulate meristem initiation by modulating auxin transport and MAX2 expression.
NDL proteins act in a signaling pathway that modulates root auxin transport and auxin gradients in part by affecting the levels of at least two auxin transport facilitators.[NDL1]
Title: Arabidopsis N-MYC DOWNREGULATED-LIKE1, a positive regulator of auxin transport in a G protein-mediated pathway.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001345216.1

Supported by ESTs:

NM_125058.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within auxin transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of auxin polar transport	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to auxin	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to jasmonic acid	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to salicylic acid	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: N-MYC downregulated-like 1

NP_200486.1

N-MYC downregulated-like 1 (NDL1); CONTAINS InterPro DOMAIN/s: Pollen specific protein SF21 (InterPro:IPR015511), Ndr (InterPro:IPR004142); BEST Arabidopsis thaliana protein match is: N-MYC downregulated-like 3 (TAIR:AT2G19620.1); Has 776 Blast hits to 775 proteins in 111 species: Archae - 2; Bacteria - 48; Metazoa - 563; Fungi - 0; Plants - 132; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

22957629..22960916

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_125058.3 → NP_200486.1 N-MYC downregulated-like 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_200486.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9FJT7

UniProtKB/TrEMBL

A0A178UI60, A0A5S9YFC3

Conserved Domains (1) summary

pfam03096
Location:21 → 305

Ndr; Ndr family
NM_001345216.1 → NP_001330516.1 N-MYC downregulated-like 1 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8BB26