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GS1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835849, updated on 18-Sep-2024

Summary

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Official Symbol
GS1
Official Full Name
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
Primary source
TAIR:AT5G57440
Locus tag
AT5G57440
See related
Araport:AT5G57440
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
GLYCEROL-3-PHOSPHATASE 2; GPP2; MUA2.2; MUA2_2
Summary
a member of haloacid dehalogenase-like hydrolase family
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Genomic context

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See GS1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Sequence:
Chromosome: 5; NC_003076.8 (23271114..23273021, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Afadin/alpha-actinin-binding protein Neighboring gene indole-3-acetic acid inducible 33 Neighboring gene homolog of X-ray repair cross complementing 3 (XRCC3) Neighboring gene muniscin carboxy-terminal mu-like domain protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence Determinants of Substrate Ambiguity in a HAD Phosphosugar Phosphatase of Arabidopsis Thaliana. Caparrós-Martín JA, et al. Biology (Basel), 2019 Oct 9. PMID 31601035, Free PMC Article
  2. Cytosolic Glutamine Synthetase Gln1;2 Is the Main Isozyme Contributing to GS1 Activity and Can Be Up-Regulated to Relieve Ammonium Toxicity. Guan M, et al. Plant Physiol, 2016 Jul. PMID 27231101, Free PMC Article
  3. Arabidopsis thaliana AtGppl and AtGpp2: two novel low molecular weight phosphatases involved in plant glycerol metabolism. Caparrós-Martín JA, et al. Plant Mol Biol, 2007 Mar. PMID 17136424
  4. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
  5. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GLN1;2 contributes to shoot GS1 activity in vegetative growth stages.
    Title: Cytosolic Glutamine Synthetase Gln1;2 Is the Main Isozyme Contributing to GS1 Activity and Can Be Up-Regulated to Relieve Ammonium Toxicity.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_125126.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables glycerol-1-phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycerol-3-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables sugar-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in glycerol biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
NP_568858.1
  • GS1; FUNCTIONS IN: hydrolase activity, catalytic activity; INVOLVED IN: metabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), HAD-superfamily hydrolase, subfamily IA, variant 3 (InterPro:IPR006402); BEST Arabidopsis thaliana protein match is: glycerol-3-phosphatase 1 (TAIR:AT4G25840.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    23271114..23273021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_125126.3 → NP_568858.1  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568858.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VZP1, Q9FKM6
    UniProtKB/TrEMBL
    A0A178UIK6, A0A5S9YFD2
    Conserved Domains (1) summary
    PLN02811
    Location:21 → 240
    PLN02811; hydrolase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VZP1.1

Gene LinkOut

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