NRPB7 DNA-directed RNA polymerase II [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: NRPB7
Official Full Name: DNA-directed RNA polymerase II
Primary source: TAIR:AT5G59180
Locus tag: AT5G59180
See related: Araport:AT5G59180
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MNC17.16; MNC17_16
Summary: Non-catalytic subunit specific to DNA-directed RNA polymerase II; the ortholog of budding yeast RPB7
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Genomic context

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See NRPB7 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 6

Sequence:: Chromosome: 5; NC_003076.8 (23883356..23885305)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The results suggest a role for promoter-proximal RNAPII stalling in predisposing genes for transcriptional activation during plant-environment interactions.
Title: Native elongation transcript sequencing reveals temperature dependent dynamics of nascent RNAPII transcription in Arabidopsis.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_125308.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of RNA polymerase II, core complex	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: DNA-directed RNA polymerase II

NP_200726.1

NRPB7; FUNCTIONS IN: DNA-directed RNA polymerase activity, RNA binding; INVOLVED IN: transcription; LOCATED IN: DNA-directed RNA polymerase II, core complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Ribosomal protein S1, RNA-binding domain (InterPro:IPR003029), RNA polymerase Rpb7, N-terminal (InterPro:IPR005576); BEST Arabidopsis thaliana protein match is: RNA polymerase Rpb7-like, N-terminal domain (TAIR:AT4G14660.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

23883356..23885305

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_125308.4 → NP_200726.1 DNA-directed RNA polymerase II [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_200726.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P38421, Q541V8

UniProtKB/TrEMBL

A0A178UBZ0, A0A5S9YFK3, A0A7G2FHB4

Conserved Domains (1) summary

PTZ00162
Location:1 → 172

PTZ00162; DNA-directed RNA polymerase II subunit 7; Provisional