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ECA1 ER-type Ca2+-ATPase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837296, updated on 18-Sep-2024

Summary

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Official Symbol
ECA1
Official Full Name
ER-type Ca2+-ATPase 1
Primary source
TAIR:AT1G07810
Locus tag
AT1G07810
See related
Araport:AT1G07810
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ACA3; ARABIDOPSIS THALIANA ER-TYPE CA2+-ATPASE 1; ATECA1; ER-TYPE CA2+-ATPASE; ER-type Ca2+-ATPase 1; F24B9.9; F24B9_9
Summary
Encodes an ER-type Ca2+-pumping ATPase.
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Genomic context

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See ECA1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Sequence:
Chromosome: 1; NC_003070.9 (2416178..2420829)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene forkhead box protein G1 Neighboring gene pseudo Neighboring gene Histone superfamily protein Neighboring gene ribosomal protein L29 family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An A/ENTH domain-containing protein functions as an adaptor for clathrin-coated vesicles on the growing cell plate in Arabidopsis root cells. Song K, et al. Plant Physiol, 2012 Jul. PMID 22635117, Free PMC Article
  2. An endoplasmic reticulum-bound Ca(2+)/Mn(2+) pump, ECA1, supports plant growth and confers tolerance to Mn(2+) stress. Wu Z, et al. Plant Physiol, 2002 Sep. PMID 12226493, Free PMC Article
  3. MIZ1 regulates ECA1 to generate a slow, long-distance phloem-transmitted Ca(2+) signal essential for root water tracking in Arabidopsis. Shkolnik D, et al. Proc Natl Acad Sci U S A, 2018 Jul 31. PMID 30012618, Free PMC Article
  4. ECA1 complements yeast mutants defective in Ca2+ pumps and encodes an endoplasmic reticulum-type Ca2+-ATPase in Arabidopsis thaliana. Liang F, et al. Proc Natl Acad Sci U S A, 1997 Aug 5. PMID 9238019, Free PMC Article
  5. Genomic comparison of P-type ATPase ion pumps in Arabidopsis and rice. Baxter I, et al. Plant Physiol, 2003 Jun. PMID 12805592, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the inhibition of ECA1 by MIZ1 changes the balance between cytosolic Ca(2+) influx and efflux and generates the cytosolic Ca(2+) signal required for water tracking.
    Title: MIZ1 regulates ECA1 to generate a slow, long-distance phloem-transmitted Ca(2+) signal essential for root water tracking in Arabidopsis.
  2. An AP180 amino-terminal homology/epsin amino-terminal homology domain-containing protein from Arabidopsis (Arabidopsis thaliana) is involved in clathrin-coated vesicle formation from the cell plate.
    Title: An A/ENTH domain-containing protein functions as an adaptor for clathrin-coated vesicles on the growing cell plate in Arabidopsis root cells.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_100655.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables P-type calcium transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables P-type calcium transporter activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables P-type calcium transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within calcium ion transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in calcium ion transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within intracellular manganese ion homeostasis IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within manganese ion transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within response to manganese ion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plant-type vacuole HDA PubMed 

General protein information

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Preferred Names
ER-type Ca2+-ATPase 1
NP_172259.1
  • ER-type Ca2+-ATPase 1 (ECA1); FUNCTIONS IN: calcium-transporting ATPase activity; INVOLVED IN: manganese ion transport, response to cadmium ion, cellular manganese ion homeostasis, calcium ion transport, response to manganese ion; LOCATED IN: endoplasmic reticulum, plasma membrane, endoplasmic reticulum membrane; EXPRESSED IN: guard cell, callus, cultured cell; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, calcium-transporting (InterPro:IPR005782), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type phosphorylation site (InterPro:IPR018303), ATPase, P-type cation-transporter, C-terminal (InterPro:IPR006068); BEST Arabidopsis thaliana protein match is: endomembrane-type CA-ATPase 4 (TAIR:AT1G07670.1); Has 52947 Blast hits to 34771 proteins in 3297 species: Archae - 1117; Bacteria - 37251; Metazoa - 4506; Fungi - 2912; Plants - 2416; Viruses - 3; Other Eukaryotes - 4742 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    2416178..2420829
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100655.4 → NP_172259.1  ER-type Ca2+-ATPase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172259.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O04987, P92939
    UniProtKB/TrEMBL
    A0A178W6B4
    Conserved Domains (1) summary
    cl21460
    Location:27 → 1042
    HAD_like; Haloacid Dehalogenase-like Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P92939.2

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