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PS1 Presenilin-1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837391, updated on 18-Sep-2024

Summary

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Official Symbol
PS1
Official Full Name
Presenilin-1
Primary source
TAIR:AT1G08700
Locus tag
AT1G08700
See related
Araport:AT1G08700
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F22O13.18; F22O13_18; Presenilin-1
Summary
Encodes a protein similar to animal presenilin whose expression is increased in response to potassium (K+) deprivation.
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Genomic context

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See PS1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_003070.9 (2769615..2771477, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ENTH/VHS family protein Neighboring gene ARF GAP-like zinc finger-containing protein ZIGA4 Neighboring gene SCR-like 3 Neighboring gene F-box family protein Neighboring gene Protein kinase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Organelles maintain spindle position in plant meiosis. Brownfield L, et al. Nat Commun, 2015 Mar 11. PMID 25757555
  2. Gamma-secretase subunits associate in intracellular membrane compartments in Arabidopsis thaliana. Smolarkiewicz M, et al. J Exp Bot, 2014 Jul. PMID 24723404, Free PMC Article
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_100743.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi-associated vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Presenilin-1
NP_172346.1
  • Presenilin-1 (PS1); INVOLVED IN: intracellular signaling pathway; LOCATED IN: endomembrane system, integral to membrane, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22A, presenilin (InterPro:IPR001108); BEST Arabidopsis thaliana protein match is: Presenilin-2 (TAIR:AT2G29900.1); Has 596 Blast hits to 445 proteins in 109 species: Archae - 4; Bacteria - 0; Metazoa - 417; Fungi - 0; Plants - 68; Viruses - 0; Other Eukaryotes - 107 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    2769615..2771477 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100743.4 → NP_172346.1  Presenilin-1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172346.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O64668, Q8L9V0
    UniProtKB/TrEMBL
    A0A178W198, A0A384LEN8, Q0V7S4
    Conserved Domains (1) summary
    pfam01080
    Location:10 → 443
    Presenilin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O64668.1

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