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MPK1 mitogen-activated protein kinase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837559, updated on 18-Sep-2024

Summary

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Official Symbol
MPK1
Official Full Name
mitogen-activated protein kinase 1
Primary source
TAIR:AT1G10210
Locus tag
AT1G10210
See related
Araport:AT1G10210
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATMPK1; F14N23.9; F14N23_9; MITOGEN-ACTIVATED PROTEIN KINASE; mitogen-activated protein kinase 1
Summary
Encodes ATMPK1.
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Genomic context

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See MPK1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (3349082..3351180)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene NEP-interacting protein, putative (DUF239) Neighboring gene GATA type zinc finger transcription factor family protein Neighboring gene ZCF37 Neighboring gene transmembrane protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis MAP Kinase Phosphatase 1 (AtMKP1) negatively regulates MPK6-mediated PAMP responses and resistance against bacteria. Anderson JC, et al. Plant J, 2011 Jul. PMID 21447069
  2. Diverse stress signals activate the C1 subgroup MAP kinases of Arabidopsis. Ortiz-Masia D, et al. FEBS Lett, 2007 May 1. PMID 17433310
  3. Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells. Mizoguchi T, et al. Plant J, 1994 Jan. PMID 8130795
  4. An Arabidopsis kinase cascade influences auxin-responsive cell expansion. Enders TA, et al. Plant J, 2017 Oct. PMID 28710770, Free PMC Article
  5. MAP kinase phosphatase1 and protein tyrosine phosphatase1 are repressors of salicylic acid synthesis and SNC1-mediated responses in Arabidopsis. Bartels S, et al. Plant Cell, 2009 Sep. PMID 19789277, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The data suggest a MKK3 * MPK1 * RBK1 phosphorylation cascade that may provide a dynamic module for altering cell expansion.
    Title: An Arabidopsis kinase cascade influences auxin-responsive cell expansion.
  2. MKP1 is a negative regulator of signaling pathways required for some, but not all, early and late pathogen-associated molecular pattern responses.
    Title: Arabidopsis MAP Kinase Phosphatase 1 (AtMKP1) negatively regulates MPK6-mediated PAMP responses and resistance against bacteria.
  3. MKP1 and PTP1 act redundantly to suppress salicylic acid and camalexin biosynthesis, and regulate growth homeostasis and PR gene expression in an MPK3- and MPK6-dependent manner.
    Title: MAP kinase phosphatase1 and protein tyrosine phosphatase1 are repressors of salicylic acid synthesis and SNC1-mediated responses in Arabidopsis.
  4. Regulation of AtMPK1/2 kinase activity in Arabidopsis might be under the control of signals involved in different kinds of stress.
    Title: Diverse stress signals activate the C1 subgroup MAP kinases of Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001035940.2
NM_001331892.1
NM_100895.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables MAP kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within auxin-activated signaling pathway TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within signal transduction IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
mitogen-activated protein kinase 1
NP_001031017.1
  • mitogen-activated protein kinase 1 (ATMPK1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase homolog 2 (TAIR:AT1G59580.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_172492.1
  • mitogen-activated protein kinase 1 (MPK1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase homolog 2 (TAIR:AT1G59580.2); Has 120133 Blast hits to 118709 proteins in 4414 species: Archae - 90; Bacteria - 12052; Metazoa - 45818; Fungi - 12226; Plants - 29321; Viruses - 480; Other Eukaryotes - 20146 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    3349082..3351180
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100895.3 → NP_172492.1  mitogen-activated protein kinase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172492.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q39021, Q9SY63
    UniProtKB/TrEMBL
    A0A178W6I4, B9DGP4
    Conserved Domains (1) summary
    cd07858
    Location:26 → 361
    STKc_TEY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TEY Mitogen-Activated Protein Kinases

  2. NM_001331892.1 → NP_001320530.1  mitogen-activated protein kinase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q39021, Q9SY63
    UniProtKB/TrEMBL
    A0A178W6I4, B9DGP4
    Conserved Domains (1) summary
    cd07858
    Location:26 → 361
    STKc_TEY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TEY Mitogen-Activated Protein Kinases

  3. NM_001035940.2 → NP_001031017.1  mitogen-activated protein kinase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031017.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q39021, Q9SY63
    UniProtKB/TrEMBL
    A0A178W6I4, B9DGP4
    Conserved Domains (1) summary
    cd07858
    Location:26 → 361
    STKc_TEY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TEY Mitogen-Activated Protein Kinases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q39021.2

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