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CYP51G1 CYTOCHROME P450 51G1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837712, updated on 18-Sep-2024

Summary

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Official Symbol
CYP51G1
Official Full Name
CYTOCHROME P450 51G1
Primary source
TAIR:AT1G11680
Locus tag
AT1G11680
See related
Araport:AT1G11680
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CYP51; CYP51A2; CYTOCHROME P450 51; CYTOCHROME P450 51A2; CYTOCHROME P450 51G1; EMB1738; embryo defective 1738; F25C20.17; F25C20_17
Summary
putative obtusifoliol 14-alpha demethylase involved in sterol biosynthesis.
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Genomic context

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See CYP51G1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (3938422..3940871)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene MATE efflux family protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene BRANCHLESS TRICHOME-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Postembryonic seedling lethality in the sterol-deficient Arabidopsis cyp51A2 mutant is partially mediated by the composite action of ethylene and reactive oxygen species. Kim HB, et al. Plant Physiol, 2010 Jan. PMID 19915013, Free PMC Article
  2. Lipid signaling in plants. Cloning and expression analysis of the obtusifoliol 14alpha-demethylase from Solanum chacoense Bitt., a pollination- and fertilization-induced gene with both obtusifoliol and lanosterol demethylase activity. O'Brien M, et al. Plant Physiol, 2005 Oct. PMID 16169959, Free PMC Article
  3. Arabidopsis cyp51 mutant shows postembryonic seedling lethality associated with lack of membrane integrity. Kim HB, et al. Plant Physiol, 2005 Aug. PMID 16040657, Free PMC Article
  4. Obtusifoliol 14alpha-demethylase (CYP51) antisense Arabidopsis shows slow growth and long life. Kushiro M, et al. Biochem Biophys Res Commun, 2001 Jul 6. PMID 11437378
  5. Cytochrome P450 CYP710A encodes the sterol C-22 desaturase in Arabidopsis and tomato. Morikawa T, et al. Plant Cell, 2006 Apr. PMID 16531502, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These results suggest that changes in membrane sterol contents and composition in the cyp51A2 mutant trigger the generation of oxidants and ethylene and eventually induce premature seedling senescence.
    Title: Postembryonic seedling lethality in the sterol-deficient Arabidopsis cyp51A2 mutant is partially mediated by the composite action of ethylene and reactive oxygen species.
  2. The Arabidopsis CYP51A2 gene encodes a functional obtusifoliol 14alpha-demethylase enzyme and plays an essential role in controlling plant growth and development by a sterol-specific pathway.
    Title: Arabidopsis cyp51 mutant shows postembryonic seedling lethality associated with lack of membrane integrity.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_101040.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sterol 14-demethylase activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy NAS
Non-traceable Author Statement
more info
  
acts_upstream_of_or_within sterol biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sterol biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in endoplasmic reticulum HDA PubMed 
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
CYTOCHROME P450 51G1
NP_172633.1
  • CYTOCHROME P450 51G1 (CYP51G1); FUNCTIONS IN: sterol 14-demethylase activity, oxygen binding; INVOLVED IN: sterol biosynthetic process, embryo development ending in seed dormancy; LOCATED IN: endoplasmic reticulum, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group IV (InterPro:IPR002403), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 707, subfamily A, polypeptide 4 (TAIR:AT3G19270.1); Has 30265 Blast hits to 30215 proteins in 1662 species: Archae - 71; Bacteria - 5605; Metazoa - 9913; Fungi - 5125; Plants - 8048; Viruses - 6; Other Eukaryotes - 1497 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    3938422..3940871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101040.4 → NP_172633.1  CYTOCHROME P450 51G1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172633.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SAA9
    UniProtKB/TrEMBL
    A0A178WII3, A0A5S9TWQ1
    Conserved Domains (1) summary
    cd11042
    Location:68 → 483
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SAA9.1

Gene LinkOut

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