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PEPC1 Pyridoxal phosphate phosphatase-related protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838347, updated on 18-Sep-2024

Summary

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Official Symbol
PEPC1
Official Full Name
Pyridoxal phosphate phosphatase-related protein
Primary source
TAIR:AT1G17710
Locus tag
AT1G17710
See related
Araport:AT1G17710
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
Arabidopsis thaliana phosphoethanolamine/phosphocholine phosphatase 1; AtPEPC1; F11A6.5; F11A6_5; phosphoethanolamine/phosphocholine phosphatase 1
Summary
Encodes a phosphoethanolamine/phosphocholine phosphatase. It is likely to be involved in the liberation of inorganic phosphate from intracellular sources. Expression is upregulated in the shoot of cax1/cax3 mutant.
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Genomic context

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See PEPC1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (6090405..6092027, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene U3 small nucleolar RNA-associated protein Neighboring gene prenylated RAB acceptor 1.F1 Neighboring gene Protein phosphatase 2A, regulatory subunit PR55 Neighboring gene vacuolar protein sorting 46.1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pi starvation-dependent regulation of ethanolamine metabolism by phosphoethanolamine phosphatase PECP1 in Arabidopsis roots. Tannert M, et al. J Exp Bot, 2018 Jan 23. PMID 29294054, Free PMC Article
  2. Arabidopsis thaliana PECP1: enzymatic characterization and structural organization of the first plant phosphoethanolamine/phosphocholine phosphatase. May A, et al. Biochim Biophys Acta, 2012 Feb. PMID 22024570
  3. The Phosphate Fast-Responsive Genes PECP1 and PPsPase1 Affect Phosphocholine and Phosphoethanolamine Content. Hanchi M, et al. Plant Physiol, 2018 Apr. PMID 29475899, Free PMC Article
  4. Arabidopsis PECP1 and PS2 are phosphate starvation-inducible phosphocholine phosphatases. Angkawijaya AE, et al. Biochem Biophys Res Commun, 2017 Dec 9. PMID 28942147
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Phosphoethanolamine hydrolysis by AtPECP1 during inorganic phosphorus starvation is required to down-regulate the energy-consuming biosynthesis of phosphocholine through the methylation pathway.
    Title: Pi starvation-dependent regulation of ethanolamine metabolism by phosphoethanolamine phosphatase PECP1 in Arabidopsis roots.
  2. Results indicate that pyrophosphate-specific phosphatase1 (PPsPase1) and phosphoethanolamine/phosphocholine phosphatase 1 (PECP1) do not influence phosphate homeostasis.
    Title: The Phosphate Fast-Responsive Genes PECP1 and PPsPase1 Affect Phosphocholine and Phosphoethanolamine Content.
  3. PECP1 and PS2 are the primary phosphocholine phosphatases in Arabidopsis and function redundantly under phosphate starvation. [PECP1]
    Title: Arabidopsis PECP1 and PS2 are phosphate starvation-inducible phosphocholine phosphatases.
  4. identification and characterization of the gene product at locus At1g17710 as phosphoethanolamine/phosphocholine phosphatase
    Title: Arabidopsis thaliana PECP1: enzymatic characterization and structural organization of the first plant phosphoethanolamine/phosphocholine phosphatase.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

NM_001084087.1
NM_101633.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables inorganic diphosphate phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphocholine phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphoethanolamine phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein tetramerization ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Pyridoxal phosphate phosphatase-related protein
NP_001077556.1
  • Pyridoxal phosphate phosphatase-related protein; FUNCTIONS IN: phosphatase activity; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate phosphatase-related (InterPro:IPR006384); BEST Arabidopsis thaliana protein match is: phosphate starvation-induced gene 2 (TAIR:AT1G73010.1); Has 346 Blast hits to 336 proteins in 99 species: Archae - 0; Bacteria - 6; Metazoa - 176; Fungi - 16; Plants - 103; Viruses - 0; Other Eukaryotes - 45 (source: NCBI BLink).
NP_173213.2
  • Pyridoxal phosphate phosphatase-related protein; FUNCTIONS IN: phosphatase activity; INVOLVED IN: metabolic process; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate phosphatase, PHOSPHO2 (InterPro:IPR016965), HAD-superfamily hydrolase, subfamily IB, PSPase-like (InterPro:IPR006383), Pyridoxal phosphate phosphatase-related (InterPro:IPR006384); BEST Arabidopsis thaliana protein match is: phosphate starvation-induced gene 2 (TAIR:AT1G73010.1); Has 360 Blast hits to 348 proteins in 105 species: Archae - 0; Bacteria - 18; Metazoa - 175; Fungi - 16; Plants - 106; Viruses - 0; Other Eukaryotes - 45 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    6090405..6092027 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101633.4 → NP_173213.2  Pyridoxal phosphate phosphatase-related protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173213.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8MQ90, Q9FZ62
    UniProtKB/TrEMBL
    A0A5S9UWI7, A0A654EAS0, A0A7G2DWX6
    Conserved Domains (1) summary
    pfam06888
    Location:7 → 239
    Put_Phosphatase; Putative Phosphatase

  2. NM_001084087.1 → NP_001077556.1  Pyridoxal phosphate phosphatase-related protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077556.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2DWX6
    Conserved Domains (2) summary
    pfam00702
    Location:29 → 154
    Hydrolase; haloacid dehalogenase-like hydrolase
    cl21460
    Location:19 → 207
    HAD_like; Haloacid Dehalogenase-like Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FZ62.1

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