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HMGB2 high mobility group B2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838658, updated on 18-Sep-2024

Summary

Official Symbol
HMGB2
Official Full Name
high mobility group B2
Primary source
TAIR:AT1G20693
Locus tag
AT1G20693
See related
Araport:AT1G20693
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
high mobility group B2; HIGH MOBILITY GROUP BETA 1; HMG BETA 1; NFD02; NFD2; NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 02; NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 2
Summary
Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha.
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Genomic context

See HMGB2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (7176747..7178895)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene SWI-SNF-related chromatin binding protein Neighboring gene ncRNA Neighboring gene high mobility group B3 Neighboring gene WUSCHEL related homeobox 14

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_001035997.1
NM_001084100.1
NM_101920.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables chromatin binding TAS
Traceable Author Statement
more info
PubMed 
enables structural constituent of chromatin TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in chromatin TAS
Traceable Author Statement
more info
PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
high mobility group B2
NP_001031074.1
  • high mobility group B2 (HMGB2); FUNCTIONS IN: chromatin binding, structural constituent of chromatin, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910), High mobility group, HMG1/HMG2, subgroup (InterPro:IPR000135); BEST Arabidopsis thaliana protein match is: high mobility group B3 (TAIR:AT1G20696.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_001077569.1
  • high mobility group B2 (HMGB2); FUNCTIONS IN: chromatin binding, structural constituent of chromatin, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910), High mobility group, HMG1/HMG2, subgroup (InterPro:IPR000135); BEST Arabidopsis thaliana protein match is: high mobility group B3 (TAIR:AT1G20696.3); Has 7109 Blast hits to 6235 proteins in 712 species: Archae - 0; Bacteria - 5; Metazoa - 5360; Fungi - 490; Plants - 580; Viruses - 7; Other Eukaryotes - 667 (source: NCBI BLink).
NP_564123.1
  • high mobility group B2 (HMGB2); FUNCTIONS IN: chromatin binding, structural constituent of chromatin, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910), High mobility group, HMG1/HMG2, subgroup (InterPro:IPR000135); BEST Arabidopsis thaliana protein match is: high mobility group B3 (TAIR:AT1G20696.3); Has 7209 Blast hits to 6316 proteins in 714 species: Archae - 2; Bacteria - 5; Metazoa - 5374; Fungi - 532; Plants - 604; Viruses - 9; Other Eukaryotes - 683 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    7176747..7178895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101920.3NP_564123.1  high mobility group B2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564123.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8MQZ3, O49596, Q2V4M2, Q9LM85
    UniProtKB/TrEMBL
    A0A178WQA7, A0A5S9VCX2, A0A654ECF0
    Conserved Domains (1) summary
    pfam00505
    Location:38106
    HMG_box; HMG (high mobility group) box
  2. NM_001084100.1NP_001077569.1  high mobility group B2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077569.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WNE2, A0A7G2DS12
    Conserved Domains (1) summary
    pfam00505
    Location:38106
    HMG_box; HMG (high mobility group) box
  3. NM_001035997.1NP_001031074.1  high mobility group B2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031074.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WNE2, A0A7G2DS12
    Conserved Domains (1) summary
    pfam00505
    Location:38106
    HMG_box; HMG (high mobility group) box