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HAF01 HAC13 protein (HAC13) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 840169, updated on 18-Sep-2024

Summary

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Official Symbol
HAF01
Official Full Name
HAC13 protein (HAC13)
Primary source
TAIR:AT1G32750
Locus tag
AT1G32750
See related
Araport:AT1G32750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F6N18.13; F6N18_13; GTD01; GTD1; HAC13; HAF1; HISTONE ACETYLTRANSFERASE OF THE CBP FAMILY 13; HISTONE ACETYLTRANSFERASE OF THE CBP FAMILY 13; HISTONE ACETYLTRANSFERASE OF THE TAFII250 FAMILY 1; TAF1; TBP-ASSOCIATED FACTOR 1
Summary
This gene is predicted to encode a histone acetyltransferase. Five lines with RNAi constructs directed against HAF1 grow normally and can produce root calli, but have defects in agrobacterium-mediated transformation.
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Genomic context

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See HAF01 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
22
Sequence:
Chromosome: 1; NC_003070.9 (11846247..11856765, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Cytochrome C oxidase polypeptide VIB family protein Neighboring gene electron carrier/iron ion-binding protein Neighboring gene SBP (S-ribonuclease binding protein) family protein Neighboring gene ncRNA Neighboring gene Glutaredoxin family protein Neighboring gene Cysteine-rich protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis TAF1 is an MRE11-interacting protein required for resistance to genotoxic stress and viability of the male gametophyte. Waterworth WM, et al. Plant J, 2015 Nov. PMID 26358508, Free PMC Article
  2. Yeast two-hybrid map of Arabidopsis TFIID. Lawit SJ, et al. Plant Mol Biol, 2007 May. PMID 17340043
  3. RNAi-mediated gene silencing reveals involvement of Arabidopsis chromatin-related genes in Agrobacterium-mediated root transformation. Crane YM, et al. Proc Natl Acad Sci U S A, 2007 Sep 18. PMID 17827277, Free PMC Article
  4. Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes. Pandey R, et al. Nucleic Acids Res, 2002 Dec 1. PMID 12466527, Free PMC Article
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

NM_103009.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables histone acetyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-mediated transformation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
HAC13 protein (HAC13)
NP_174552.1
  • HAF01; FUNCTIONS IN: histone acetyltransferase activity, DNA binding; INVOLVED IN: DNA mediated transformation; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TAFII-230 TBP-binding (InterPro:IPR009067), Ubiquitin (InterPro:IPR000626), Ubiquitin supergroup (InterPro:IPR019955), Bromodomain, conserved site (InterPro:IPR018359), Bromodomain (InterPro:IPR001487); BEST Arabidopsis thaliana protein match is: histone acetyltransferase of the TAFII250 family 2 (TAIR:AT3G19040.1); Has 22854 Blast hits to 14376 proteins in 1001 species: Archae - 24; Bacteria - 596; Metazoa - 11292; Fungi - 2677; Plants - 2799; Viruses - 159; Other Eukaryotes - 5307 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    11846247..11856765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_103009.4 → NP_174552.1  HAC13 protein (HAC13) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_174552.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LRK9, Q9LPI9
    UniProtKB/TrEMBL
    A0A5S9WIK6, A0A654EES7
    Conserved Domains (6) summary
    cd04369
    Location:1806 → 1901
    Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    smart00213
    Location:661 → 730
    UBQ; Ubiquitin homologues
    pfam09247
    Location:27 → 64
    TBP-binding; TATA box-binding protein binding
    pfam12157
    Location:578 → 1146
    DUF3591; Protein of unknown function (DUF3591)
    pfam15288
    Location:1399 → 1432
    zf-CCHC_6; Zinc knuckle
    cl00155
    Location:661 → 733
    UBQ; Ubiquitin-like proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8LRK9.1

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