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THO5 THO complex, subunit 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 841093, updated on 18-Sep-2024

Summary

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Official Symbol
THO5
Official Full Name
THO complex, subunit 5
Primary source
TAIR:AT1G45233
Locus tag
AT1G45233
See related
Araport:AT1G45233
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtTHO5
Summary
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
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Genomic context

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See THO5 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (17152896..17154843)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene uncharacterized protein Neighboring gene tRNA-Pro Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Putative Arabidopsis THO/TREX mRNA export complex is involved in transgene and endogenous siRNA biosynthesis. Yelina NE, et al. Proc Natl Acad Sci U S A, 2010 Aug 3. PMID 20634427, Free PMC Article
  2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_202250.3

Gene Ontology Provided by TAIR

Component Evidence Code Pubs
part_of THO complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
THO complex, subunit 5
NP_973979.2
  • THO5; CONTAINS InterPro DOMAIN/s: THO complex, subunit 5 (InterPro:IPR019163); BEST Arabidopsis thaliana protein match is: THO complex, subunit 5 (TAIR:AT5G42920.2); Has 351 Blast hits to 349 proteins in 134 species: Archae - 0; Bacteria - 10; Metazoa - 158; Fungi - 80; Plants - 53; Viruses - 0; Other Eukaryotes - 50 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    17152896..17154843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_202250.3 → NP_973979.2  THO complex, subunit 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_973979.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4HRC1
    UniProtKB/TrEMBL
    A0A178W8W4, A0A5S9WPI2, A0A654EHU9
    Conserved Domains (1) summary
    pfam09766
    Location:67 → 403
    FimP; Fms-interacting protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4HRC1.1

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