NRAMP2 NRAMP metal ion transporter 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: NRAMP2
Official Full Name: NRAMP metal ion transporter 2
Primary source: TAIR:AT1G47240
Locus tag: AT1G47240
See related: Araport:AT1G47240
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATNRAMP2; F8G22.4; F8G22_4; NRAMP metal ion transporter 2
Summary: Member of the NRAMP2 gene family of metal ion transporters.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

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NRAMP2 is required for the detoxification of reactive oxygen species.
Title: Intracellular Distribution of Manganese by the Trans-Golgi Network Transporter NRAMP2 Is Critical for Photosynthesis and Cellular Redox Homeostasis.
Under Mn-deficient conditions, increased accumulation of hydrogen peroxide (H2 O2 ) is partially responsible for the root growth inhibition and NRAMP2 is involved in remobilization of manganese (Mn) in Golgi for root growth.
Title: NRAMP2, a trans-Golgi network-localized manganese transporter, is required for Arabidopsis root growth under manganese deficiency.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_103618.3

Function	Evidence Code	Pubs
enables inorganic anion transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables manganese ion transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables manganese ion transmembrane transporter activity	IGI Inferred from Genetic Interaction more info	PubMed
enables metal ion transmembrane transporter activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to manganese ion	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within intracellular monoatomic cation homeostasis	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within manganese ion transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within manganese ion transport	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within metal ion transport	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within positive regulation of unidimensional cell growth	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within root hair elongation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within root morphogenesis	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info
located_in trans-Golgi network	IDA Inferred from Direct Assay more info	PubMed

NP_175157.1

NRAMP metal ion transporter 2 (NRAMP2); FUNCTIONS IN: inorganic anion transmembrane transporter activity, metal ion transmembrane transporter activity; INVOLVED IN: cellular metal ion homeostasis, metal ion transport; LOCATED IN: membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Natural resistance-associated macrophage protein (InterPro:IPR001046); BEST Arabidopsis thaliana protein match is: natural resistance-associated macrophage protein 3 (TAIR:AT2G23150.1); Has 4906 Blast hits to 4864 proteins in 1503 species: Archae - 114; Bacteria - 3503; Metazoa - 369; Fungi - 260; Plants - 341; Viruses - 0; Other Eukaryotes - 319 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain