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IAR3 peptidase M20/M25/M40 family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 841602, updated on 18-Sep-2024

Summary

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Official Symbol
IAR3
Official Full Name
peptidase M20/M25/M40 family protein
Primary source
TAIR:AT1G51760
Locus tag
AT1G51760
See related
Araport:AT1G51760
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F19C24.4; F19C24_4; IAA-ALA HYDROLASE; IAA-ALANINE RESISTANT 3; JASMONIC ACID RESPONSIVE 3; JR3
Summary
encodes a member of the six Arabidopsis IAA-amino acid conjugate hydrolase subfamily and conjugates and conjugates IAA-Ala in vitro. Gene is expressed most strongly in roots, stems, and flowers.
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Genomic context

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See IAR3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Sequence:
Chromosome: 1; NC_003070.9 (19199351..19201707)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Tudor/PWWP/MBT superfamily protein Neighboring gene pseudo Neighboring gene Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein Neighboring gene IAA-amino acid hydrolase ILR1-like 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Role of Cysteine Residues in Redox Regulation and Protein Stability of Arabidopsis thaliana Starch Synthase 1. Skryhan K, et al. PLoS One, 2015. PMID 26367870, Free PMC Article
  2. IAA-Ala Resistant3, an evolutionarily conserved target of miR167, mediates Arabidopsis root architecture changes during high osmotic stress. Kinoshita N, et al. Plant Cell, 2012 Sep. PMID 22960911, Free PMC Article
  3. The amidohydrolases IAR3 and ILL6 contribute to jasmonoyl-isoleucine hormone turnover and generate 12-hydroxyjasmonic acid upon wounding in Arabidopsis leaves. Widemann E, et al. J Biol Chem, 2013 Nov 1. PMID 24052260, Free PMC Article
  4. IAR3 encodes an auxin conjugate hydrolase from Arabidopsis. Davies RT, et al. Plant Cell, 1999 Mar. PMID 10072397, Free PMC Article
  5. A downstream mediator in the growth repression limb of the jasmonate pathway. Yan Y, et al. Plant Cell, 2007 Aug. PMID 17675405, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data suggest distinct physiological roles of redox-active Cys residues in AtSS1 including diurnal activity regulation directly linked to photosynthesis as well as stress-related protection of AtSS1.
    Title: The Role of Cysteine Residues in Redox Regulation and Protein Stability of Arabidopsis thaliana Starch Synthase 1.
  2. The amidohydrolases IAR3 and ILL6 contribute to jasmonoyl-isoleucine hormone turnover and generate 12-hydroxyjasmonic acid upon wounding in Arabidopsis leaves.
    Title: The amidohydrolases IAR3 and ILL6 contribute to jasmonoyl-isoleucine hormone turnover and generate 12-hydroxyjasmonic acid upon wounding in Arabidopsis leaves.
  3. IAR3 is a regulator of root architecture changes in osmotic stress and drought tolerance.
    Title: IAA-Ala Resistant3, an evolutionarily conserved target of miR167, mediates Arabidopsis root architecture changes during high osmotic stress.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_104055.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables IAA-Ala conjugate hydrolase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in auxin metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to wounding IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in endoplasmic reticulum HDA PubMed 
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
peptidase M20/M25/M40 family protein
NP_175587.1
  • IAA-ALANINE RESISTANT 3 (IAR3); FUNCTIONS IN: metallopeptidase activity, IAA-Ala conjugate hydrolase activity; INVOLVED IN: proteolysis, response to wounding; LOCATED IN: endoplasmic reticulum, plasma membrane; EXPRESSED IN: callus; CONTAINS InterPro DOMAIN/s: Peptidase M20 (InterPro:IPR002933), Peptidase M20D, mername-AA028/carboxypeptidase Ss1 (InterPro:IPR017439), Peptidase M20, dimerisation (InterPro:IPR011650), Peptidase M20D, amidohydrolase (InterPro:IPR010168); BEST Arabidopsis thaliana protein match is: IAA-leucine resistant (ILR)-like gene 5 (TAIR:AT1G51780.1); Has 13368 Blast hits to 13360 proteins in 1987 species: Archae - 133; Bacteria - 9793; Metazoa - 95; Fungi - 261; Plants - 323; Viruses - 0; Other Eukaryotes - 2763 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    19199351..19201707
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104055.4 → NP_175587.1  peptidase M20/M25/M40 family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_175587.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O04373, O81642
    UniProtKB/TrEMBL
    A0A178W8I8, A0A5S9WNW0
    Conserved Domains (1) summary
    cd08017
    Location:48 → 423
    M20_IAA_Hyd; M20 Peptidase Indole-3-acetic acid amino acid hydrolase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O04373.2

Gene LinkOut

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