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KAS III 3-ketoacyl-acyl carrier protein synthase III [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842561, updated on 18-Sep-2024

Summary

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Official Symbol
KAS III
Official Full Name
3-ketoacyl-acyl carrier protein synthase III
Primary source
TAIR:AT1G62640
Locus tag
AT1G62640
See related
Araport:AT1G62640
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
3-ketoacyl-acyl carrier protein synthase III; 3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III; T3P18.20; T3P18_20
Summary
3-ketoacyl-acyl carrier protein synthase III (KAS III)
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Genomic context

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See KAS III in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (23192146..23195103)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene Flavin-binding monooxygenase family protein Neighboring gene Disease resistance protein (CC-NBS-LRR class) family Neighboring gene miscRNA Neighboring gene Glycosyl hydrolases family 32 protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo biosynthesis of fatty acids plays critical roles in the response of the photosynthetic machinery to low temperature in Arabidopsis. Takami T, et al. Plant Cell Physiol, 2010 Aug. PMID 20547590
  2. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
  3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. kas3 mutants are defective in thylakoid protein accumulation at low temperature.
    Title: De novo biosynthesis of fatty acids plays critical roles in the response of the photosynthetic machinery to low temperature in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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NM_001036144.2
NM_104942.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3-oxoacyl-[acyl-carrier-protein] synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables beta-ketoacyl-acyl-carrier-protein synthase III activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma HDA PubMed 

General protein information

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Preferred Names
3-ketoacyl-acyl carrier protein synthase III
NP_001031221.1
  • 3-ketoacyl-acyl carrier protein synthase III (KAS III); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, 3-oxoacyl-[acyl-carrier-protein] synthase activity, catalytic activity; INVOLVED IN: lipid biosynthetic process, metabolic process, fatty acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III (InterPro:IPR013751), Beta-ketoacyl-acyl carrier protein synthase III (FabH) (InterPro:IPR004655); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_176452.1
  • 3-ketoacyl-acyl carrier protein synthase III (KAS III); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, 3-oxoacyl-[acyl-carrier-protein] synthase activity, catalytic activity; INVOLVED IN: lipid biosynthetic process, metabolic process, fatty acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III (InterPro:IPR013751), Beta-ketoacyl-acyl carrier protein synthase III (FabH) (InterPro:IPR004655); Has 11800 Blast hits to 11794 proteins in 2811 species: Archae - 187; Bacteria - 7763; Metazoa - 5; Fungi - 2; Plants - 1625; Viruses - 0; Other Eukaryotes - 2218 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    23192146..23195103
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104942.4 → NP_176452.1  3-ketoacyl-acyl carrier protein synthase III [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176452.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P49243, P93722, Q9SI84, Q9SXD3
    UniProtKB/TrEMBL
    A0A5S9WS16, A0A654EW34, B9DHF9
    Conserved Domains (2) summary
    PLN02326
    Location:23 → 403
    PLN02326; 3-oxoacyl-[acyl-carrier-protein] synthase III
    cd00830
    Location:69 → 401
    KAS_III; Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl ...

  2. NM_001036144.2 → NP_001031221.1  3-ketoacyl-acyl carrier protein synthase III [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031221.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P49243, P93722, Q9SI84, Q9SXD3
    UniProtKB/TrEMBL
    A0A5S9WS16, A0A654EW34, B9DHF9
    Conserved Domains (2) summary
    PLN02326
    Location:23 → 403
    PLN02326; 3-oxoacyl-[acyl-carrier-protein] synthase III
    cd00830
    Location:69 → 401
    KAS_III; Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P49243.2

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