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LPLAT2 MBOAT (membrane bound O-acyl transferase) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842608, updated on 18-Sep-2024

Summary

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Official Symbol
LPLAT2
Official Full Name
MBOAT (membrane bound O-acyl transferase) family protein
Primary source
TAIR:AT1G63050
Locus tag
AT1G63050
See related
Araport:AT1G63050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtLPLAT2; F16M19.14; F16M19_14; LPCAT2; lysophosphatidylcholine acyltransferase 2; lysophospholipid acyltransferase 2
Summary
Encodes a lysophosphatidylcholine acyltransferase (LPCAT). Participates in the Lands cycle in developing seeds. Involved in triacylglycerol biosynthesis.
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Genomic context

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See LPLAT2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (23375877..23378355, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ribosome biogenesis NEP1-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Natural variation in acyl editing is a determinant of seed storage oil composition. Menard GN, et al. Sci Rep, 2018 Nov 26. PMID 30478395, Free PMC Article
  2. Castor LPCAT and PDAT1A Act in Concert to Promote Transacylation of Hydroxy-Fatty Acid onto Triacylglycerol. Lunn D, et al. Plant Physiol, 2020 Oct. PMID 32737074, Free PMC Article
  3. On the Role of DGAT1 in Seed Glycerolipid Metabolic Network and Critical Stages of Plant Development in Arabidopsis. Wang L, et al. Lipids, 2020 Sep. PMID 32106336
  4. Metabolic interactions between the Lands cycle and the Kennedy pathway of glycerolipid synthesis in Arabidopsis developing seeds. Wang L, et al. Plant Cell, 2012 Nov. PMID 23150634, Free PMC Article
  5. Acyl editing and headgroup exchange are the major mechanisms that direct polyunsaturated fatty acid flux into triacylglycerols. Bates PD, et al. Plant Physiol, 2012 Nov. PMID 22932756, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. On the Role of DGAT1 in Seed Glycerolipid Metabolic Network and Critical Stages of Plant Development in Arabidopsis.
    Title: On the Role of DGAT1 in Seed Glycerolipid Metabolic Network and Critical Stages of Plant Development in Arabidopsis.
  2. Castor LPCAT and PDAT1A Act in Concert to Promote Transacylation of Hydroxy-Fatty Acid onto Triacylglycerol.
    Title: Castor LPCAT and PDAT1A Act in Concert to Promote Transacylation of Hydroxy-Fatty Acid onto Triacylglycerol.
  3. Natural variation in LPCAT231-33 is a determinant of seed storage oil composition in Arabidopsis.
    Title: Natural variation in acyl editing is a determinant of seed storage oil composition.
  4. Arabidopsis thaliana LPCATs, LPCAT1 and LPCAT2, participate in the Lands cycle in developing seeds.
    Title: Metabolic interactions between the Lands cycle and the Kennedy pathway of glycerolipid synthesis in Arabidopsis developing seeds.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_104983.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 1-acylglycerophosphocholine O-acyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables acyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables lysophospholipid acyltransferase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within galactolipid biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within glycerolipid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within phospholipid biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within triglyceride biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within triglyceride metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
MBOAT (membrane bound O-acyl transferase) family protein
NP_176493.1
  • MBOAT (membrane bound O-acyl transferase) family protein; FUNCTIONS IN: acyltransferase activity; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Membrane bound O-acyl transferase, MBOAT (InterPro:IPR004299); BEST Arabidopsis thaliana protein match is: MBOAT (membrane bound O-acyl transferase) family protein (TAIR:AT1G12640.1); Has 1074 Blast hits to 1071 proteins in 250 species: Archae - 0; Bacteria - 147; Metazoa - 624; Fungi - 142; Plants - 47; Viruses - 0; Other Eukaryotes - 114 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    23375877..23378355 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104983.5 → NP_176493.1  MBOAT (membrane bound O-acyl transferase) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176493.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9CAN8
    UniProtKB/TrEMBL
    A0A178WEX3, A0A5S9WRL2
    Conserved Domains (1) summary
    PLN02332
    Location:2 → 465
    PLN02332; membrane bound O-acyl transferase (MBOAT) family protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CAN8.1

Gene LinkOut

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