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SPPL2 SIGNAL PEPTIDE PEPTIDASE-LIKE 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842673, updated on 18-Sep-2024

Summary

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Official Symbol
SPPL2
Official Full Name
SIGNAL PEPTIDE PEPTIDASE-LIKE 2
Primary source
TAIR:AT1G63690
Locus tag
AT1G63690
See related
Araport:AT1G63690
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATSPPL2; F24D7.12; F24D7_12; SIGNAL PEPTIDE PEPTIDASE-LIKE 2
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Genomic context

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See SPPL2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Sequence:
Chromosome: 1; NC_003070.9 (23618012..23622396)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF3741) Neighboring gene ALBINO OR PALE-GREEN 13 Neighboring gene Protein kinase superfamily protein Neighboring gene cytochrome P450, family 86, subfamily A, polypeptide 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Signal peptide peptidase and its homologs in Arabidopsis thaliana--plant tissue-specific expression and distinct subcellular localization. Tamura T, et al. FEBS J, 2008 Jan. PMID 18067581
  2. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_105046.3
NM_202353.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISM
Inferred from Sequence Model
more info
  
located_in endosome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
SIGNAL PEPTIDE PEPTIDASE-LIKE 2
NP_564815.1
  • SIGNAL PEPTIDE PEPTIDASE-LIKE 2 (SPPL2); FUNCTIONS IN: peptidase activity, aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: endosome, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22B, signal peptide peptidase (InterPro:IPR007369); BEST Arabidopsis thaliana protein match is: SIGNAL PEPTIDE PEPTIDASE-LIKE 4 (TAIR:AT1G01650.1); Has 1779 Blast hits to 1755 proteins in 292 species: Archae - 1; Bacteria - 179; Metazoa - 755; Fungi - 159; Plants - 440; Viruses - 0; Other Eukaryotes - 245 (source: NCBI BLink).
NP_974082.1
  • SIGNAL PEPTIDE PEPTIDASE-LIKE 2 (SPPL2); FUNCTIONS IN: peptidase activity, aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: endosome, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22B, signal peptide peptidase (InterPro:IPR007369); BEST Arabidopsis thaliana protein match is: SIGNAL PEPTIDE PEPTIDASE-LIKE 4 (TAIR:AT1G01650.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    23618012..23622396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105046.3 → NP_564815.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564815.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LCK4, Q8W469, Q9CAD4
    UniProtKB/TrEMBL
    A0A178WA20, A0A5S9WS38
    Conserved Domains (2) summary
    cd02132
    Location:46 → 184
    PA_GO-like; PA_GO-like: Protease-associated domain containing proteins like Arabidopsis thaliana growth-on protein GRO10. This group contains various PA domain-containing proteins similar to the functionally uncharacterized Arabidopsis GRO10. The PA domain may be a ...
    pfam04258
    Location:245 → 525
    Peptidase_A22B; Signal peptide peptidase

  2. NM_202353.1 → NP_974082.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974082.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WA20, A0A5S9WS38, F4I3Q0
    Conserved Domains (2) summary
    cd02132
    Location:46 → 184
    PA_GO-like; PA_GO-like: Protease-associated domain containing proteins like Arabidopsis thaliana growth-on protein GRO10. This group contains various PA domain-containing proteins similar to the functionally uncharacterized Arabidopsis GRO10. The PA domain may be a ...
    pfam04258
    Location:245 → 525
    Peptidase_A22B; Signal peptide peptidase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8W469.1

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