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FMO GS-OX1 flavin-monooxygenase glucosinolate S-oxygenase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842897, updated on 18-Sep-2024

Summary

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Official Symbol
FMO GS-OX1
Official Full Name
flavin-monooxygenase glucosinolate S-oxygenase 1
Primary source
TAIR:AT1G65860
Locus tag
AT1G65860
See related
Araport:AT1G65860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F12P19.2; F12P19_2; flavin-monooxygenase glucosinolate S-oxygenase 1
Summary
belongs to the flavin-monooxygenase (FMO) family, encodes a glucosinolate S-oxygenase that catalyzes the conversion of methylthioalkyl glucosinolates to methylsulfinylalkyl glucosinolates
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Genomic context

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See FMO GS-OX1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Sequence:
Chromosome: 1; NC_003070.9 (24498954..24502776, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene polyamine oxidase 4 Neighboring gene uncharacterized protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene Disease resistance-responsive (dirigent-like protein) family protein Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a flavin-monooxygenase as the S-oxygenating enzyme in aliphatic glucosinolate biosynthesis in Arabidopsis. Hansen BG, et al. Plant J, 2007 Jun. PMID 17461789
  2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_105258.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3-methylthiopropyl glucosinolate S-oxygenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables 4-methylthiopropyl glucosinolate S-oxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 4-methylthiopropyl glucosinolate S-oxygenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables 5-methylthiopropyl glucosinolate S-oxygenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables 6-methylthiopropyl glucosinolate S-oxygenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables 7-methylthiopropyl glucosinolate S-oxygenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables 8-methylthiopropyl glucosinolate S-oxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 8-methylthiopropyl glucosinolate S-oxygenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables N,N-dimethylaniline monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glucosinolate biosynthetic process from homomethionine IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
flavin-monooxygenase glucosinolate S-oxygenase 1
NP_176761.1
  • flavin-monooxygenase glucosinolate S-oxygenase 1 (FMO GS-OX1); CONTAINS InterPro DOMAIN/s: Flavin-containing monooxygenase FMO (InterPro:IPR000960), Flavin-containing monooxygenase-like (InterPro:IPR020946); BEST Arabidopsis thaliana protein match is: flavin-monooxygenase glucosinolate S-oxygenase 2 (TAIR:AT1G62540.1); Has 13357 Blast hits to 12951 proteins in 1760 species: Archae - 39; Bacteria - 7207; Metazoa - 1086; Fungi - 1434; Plants - 770; Viruses - 0; Other Eukaryotes - 2821 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    24498954..24502776 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105258.3 → NP_176761.1  flavin-monooxygenase glucosinolate S-oxygenase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176761.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SS04
    UniProtKB/TrEMBL
    A0A178W5U2, A0A5S9WSH9, A0A654ERG4
    Conserved Domains (1) summary
    PLN02172
    Location:1 → 459
    PLN02172; flavin-containing monooxygenase FMO GS-OX
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SS04.1

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