U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

APL Homeodomain-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 844281, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
APL
Official Full Name
Homeodomain-like superfamily protein
Primary source
TAIR:AT1G79430
Locus tag
AT1G79430
See related
Araport:AT1G79430
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ALTERED PHLOEM DEVELOPMENT; T8K14.15; T8K14_15; WDY; WOODY
Summary
Encodes gene product that is required for several aspects of phloem development in the root: (1) the specific divisions organizing the phloem pole, (2) sieve element differentiation and (3) the expression of a companion-specific gene. Mutant has a defect in the organization of phloem poles in the root. apl seedlings have a short, determinate root with only occasional lateral branches.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See APL in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Sequence:
Chromosome: 1; NC_003070.9 (29877228..29879279, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene organic cation/carnitine transporter5 Neighboring gene C-type mannose receptor (DUF620) Neighboring gene aldehyde dehydrogenase 5F1 Neighboring gene ALA-interacting subunit 5

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. FE Controls the Transcription of Downstream Flowering Regulators Through Two Distinct Mechanisms in Leaf Phloem Companion Cells. Shibuta M, et al. Plant Cell Physiol, 2017 Nov 1. PMID 29036620
  2. APL regulates vascular tissue identity in Arabidopsis. Bonke M, et al. Nature, 2003 Nov 13. PMID 14614507
  3. FE, a phloem-specific Myb-related protein, promotes flowering through transcriptional activation of FLOWERING LOCUS T and FLOWERING LOCUS T INTERACTING PROTEIN 1. Abe M, et al. Plant J, 2015 Sep. PMID 26239308
  4. Plant development. Arabidopsis NAC45/86 direct sieve element morphogenesis culminating in enucleation. Furuta KM, et al. Science, 2014 Aug 22. PMID 25081480
  5. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. APL (FE protein) regulates the transcription of FT and florigen transporter genes in different manners in leaf phloem companion cells.
    Title: FE Controls the Transcription of Downstream Flowering Regulators Through Two Distinct Mechanisms in Leaf Phloem Companion Cells.
  2. The FE protein regulates the expression of FTIP1 involved in FT transport. FE protein promotes flowering through transcriptional activation of FT and Ftip1.
    Title: FE, a phloem-specific Myb-related protein, promotes flowering through transcriptional activation of FLOWERING LOCUS T and FLOWERING LOCUS T INTERACTING PROTEIN 1.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help
NM_106591.2
NM_179574.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within phloem development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within xylem development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Homeodomain-like superfamily protein
NP_565209.1
  • ALTERED PHLOEM DEVELOPMENT (APL); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT3G12730.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_849905.1
  • ALTERED PHLOEM DEVELOPMENT (APL); CONTAINS InterPro DOMAIN/s: Myb, DNA-binding (InterPro:IPR014778), Homeodomain-like (InterPro:IPR009057), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447), Homeodomain-related (InterPro:IPR012287), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT3G12730.1); Has 1662 Blast hits to 1649 proteins in 60 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 1644; Viruses - 0; Other Eukaryotes - 16 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    29877228..29879279 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_179574.3 → NP_849905.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849905.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DFC9, Q94AW3, Q9SAK5
    UniProtKB/TrEMBL
    A0A5S9WVS7, A0A654F195
    Conserved Domains (2) summary
    TIGR01557
    Location:34 → 90
    myb_SHAQKYF; myb-like DNA-binding domain, SHAQKYF class
    pfam14379
    Location:130 → 169
    Myb_CC_LHEQLE; MYB-CC type transfactor, LHEQLE motif

  2. NM_106591.2 → NP_565209.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565209.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9WVS7
    Conserved Domains (2) summary
    pfam14379
    Location:65 → 102
    Myb_CC_LHEQLE; MYB-CC type transfactor, LHEQLE motif
    cl21498
    Location:2 → 25
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SAK5.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.