EMB2753 tetratricopeptide repeat (TPR)-containing protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: EMB2753
Official Full Name: tetratricopeptide repeat (TPR)-containing protein
Primary source: TAIR:AT1G80410
Locus tag: AT1G80410
See related: Araport:AT1G80410
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: EMBRYO DEFECTIVE 2753; OMA; OMISHA; T21F11.26; T21F11_26
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Genomic context

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See EMB2753 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 26

Sequence:: Chromosome: 1; NC_003070.9 (30227485..30235087, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

N-terminal acetylation by the NatA complex acts as a cellular surveillance mechanism during stress and that imprinting of the proteome by NatA is an important switch for the control of metabolism, development and cellular stress responses downstream of abscisic acid. [NAA15]
Title: Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001198519.1

Supported by ESTs:

NM_106690.6

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within embryo development ending in seed dormancy	NAS Non-traceable Author Statement more info
acts_upstream_of_or_within response to water deprivation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of NatA complex	IPI Inferred from Physical Interaction more info	PubMed
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in plasmodesma	HDA more info	PubMed

General protein information

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Preferred Names: tetratricopeptide repeat (TPR)-containing protein

NP_001185448.1

EMBRYO DEFECTIVE 2753 (EMB2753); FUNCTIONS IN: binding; INVOLVED IN: embryo development ending in seed dormancy; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), N-terminal acetyltransferase A, auxiliary subunit (InterPro:IPR021183), Tetratricopeptide repeat (InterPro:IPR019734).

NP_178157.2

EMBRYO DEFECTIVE 2753 (EMB2753); FUNCTIONS IN: binding; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734), N-terminal acetyltransferase A, auxiliary subunit (InterPro:IPR021183); Has 4153 Blast hits to 3182 proteins in 554 species: Archae - 484; Bacteria - 1303; Metazoa - 580; Fungi - 247; Plants - 139; Viruses - 3; Other Eukaryotes - 1397 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

30227485..30235087 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_106690.6 → NP_178157.2 tetratricopeptide repeat (TPR)-containing protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_178157.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8VZM1, Q9M8L0

UniProtKB/TrEMBL

A0A178W823, A0A5S9WW46, A0A654EVS7

Conserved Domains (3) summary

TIGR02917
Location:3 → 260

PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein

sd00006
Location:44 → 71

TPR; TPR repeat [structural motif]

pfam12569
Location:186 → 693

NARP1; NMDA receptor-regulated protein 1
NM_001198519.1 → NP_001185448.1 tetratricopeptide repeat (TPR)-containing protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001185448.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178W823, F4HS68

Conserved Domains (4) summary

sd00006
Location:44 → 71

TPR; TPR repeat [structural motif]

pfam00515
Location:80 → 110

TPR_1; Tetratricopeptide repeat

pfam12569
Location:186 → 693

NARP1; NMDA receptor-regulated protein 1

pfam13414
Location:79 → 142

TPR_11; TPR repeat