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SUF16 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850374, updated on 4-Jan-2025

Summary

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Official Symbol
SUF16
Primary source
SGD:S000006575
Locus tag
YNCC0007C
See related
AllianceGenome:SGD:S000006575
Gene type
tRNA
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables ribosome binding activity and translation repressor activity. Involved in regulation of translation in response to stress. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See SUF16 in Genome Data Viewer
Location:
chromosome: III
Sequence:
Chromosome: III; NC_001135.5 (142701..142771, complement)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene Cto1p Neighboring gene ncRNA Neighboring gene RNA-binding ribosome assembly factor RBP95 Neighboring gene Cwh43p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yeast frameshift suppressor gene SUF16-1 encodes an altered glycine tRNA containing the four-base anticodon 3'-CCCG-5'. Gaber RF, et al. Gene, 1982 Sep. PMID 6293925
  2. Frameshift suppressor mutations affecting the major glycine transfer RNAs of Saccharomyces cerevisiae. Mendenhall MD, et al. J Mol Biol, 1987 Mar 5. PMID 3039147
  3. Frameshift suppression in Saccharomyces cerevisiae. IV. New suppressors among spontaneous co-revertants of the Group II his4-206 and leu 2-3 frameshift mutations. Gaber RF, et al. Genetics, 1982 Jul-Aug. PMID 6757051, Free PMC Article
  4. The yeast Ty1 retrotransposon requires components of the nuclear pore complex for transcription and genomic integration. Manhas S, et al. Nucleic Acids Res, 2018 Apr 20. PMID 29514267, Free PMC Article
  5. tRNA-derived short RNAs bind to Saccharomyces cerevisiae ribosomes in a stress-dependent manner and inhibit protein synthesis in vitro. Bąkowska-Żywicka K, et al. FEMS Yeast Res, 2016 Sep. PMID 27609601, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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  • Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE analysis;can mutate to suppress +1 frameshift mutations in glycine codons

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ribosome binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables translation repressor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables triplet codon-amino acid adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables triplet codon-amino acid adaptor activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of translation in response to stress IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational elongation IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IC
Inferred by Curator
more info
 PubMed 

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