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AHC2 Ahc2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850443, updated on 4-Jan-2025

Summary

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Official Symbol
AHC2
Official Full Name
Ahc2p
Primary source
SGD:S000000678
Locus tag
YCR082W
See related
AllianceGenome:SGD:S000000678; FungiDB:YCR082W; VEuPathDB:YCR082W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of ADA complex. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See AHC2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_001135.5 (258883..259269)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene type 2C protein phosphatase PTC6 Neighboring gene Srb8p Neighboring gene Trx3p Neighboring gene chromatin-silencing transcriptional regulator TUP1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptional activators in yeast. Titz B, et al. Nucleic Acids Res, 2006. PMID 16464826, Free PMC Article
  2. Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae. Eustice M, et al. Genetics, 2014 Apr. PMID 24532730, Free PMC Article
  3. Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress. Poli J, et al. Genes Dev, 2016 Feb 1. PMID 26798134, Free PMC Article
  4. Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles. Decourty L, et al. Proc Natl Acad Sci U S A, 2008 Apr 15. PMID 18408161, Free PMC Article
  5. The complete DNA sequence of yeast chromosome III. Oliver SG, et al. Nature, 1992 May 7. PMID 1574125

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables transcription regulator activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of ADA complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of ADA complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ahc2p
NP_010005.1
  • Component of the ADA histone acetyltransferase complex; Ahc2p and Ahc1p are unique to the ADA complex and not shared with the related SAGA and SLIK complexes; may tether Ahc1p to the complex

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    258883..259269
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178788.1 → NP_010005.1  TPA: Ahc2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010005.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VR83, P25649
    UniProtKB/TrEMBL
    A6ZTQ4, B3LUD6, C7GUW6, C8Z4G9, G2WA90, N1P972
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25649.1

Gene LinkOut

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