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IGD1 Igd1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850572, updated on 4-Jan-2025

Summary

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Official Symbol
IGD1
Official Full Name
Igd1p
Primary source
SGD:S000001913
Locus tag
YFR017C
See related
AllianceGenome:SGD:S000001913; FungiDB:YFR017C; VEuPathDB:YFR017C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables enzyme inhibitor activity. Involved in negative regulation of glycogen catabolic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See IGD1 in Genome Data Viewer
Location:
chromosome: VI
Exon count:
1
Sequence:
Chromosome: VI; NC_001138.5 (182274..182861, complement)

Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene Aip5p Neighboring gene tRNA-Gly Neighboring gene uncharacterized protein Neighboring gene 1-phosphatidylinositol-3-phosphate 5-kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001138.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Saccharomyces cerevisiae fermentation stress response protein Igd1p/Yfr017p regulates glycogen levels by inhibiting the glycogen debranching enzyme. Walkey CJ, et al. FEMS Yeast Res, 2011 Sep. PMID 21585652
  2. Mutations of the TATA-binding protein confer enhanced tolerance to hyperosmotic stress in Saccharomyces cerevisiae. Kim NR, et al. Appl Microbiol Biotechnol, 2013 Sep. PMID 23709042
  3. Construction of Saccharomyces cerevisiae strains with enhanced ethanol tolerance by mutagenesis of the TATA-binding protein gene and identification of novel genes associated with ethanol tolerance. Yang J, et al. Biotechnol Bioeng, 2011 Aug. PMID 21437883
  4. Combining chemical genetics and proteomics to identify protein kinase substrates. Dephoure N, et al. Proc Natl Acad Sci U S A, 2005 Dec 13. PMID 16330754, Free PMC Article
  5. Global protein expression profiling of budding yeast in response to DNA damage. Lee MW, et al. Yeast, 2007 Mar. PMID 17351896

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables enzyme inhibitor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables enzyme inhibitor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of glycogen catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Igd1p
NP_116672.1
  • Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity; required for normal intracellular accumulation of glycogen; phosphorylated in vivo; expression increases during wine fermentation; protein abundance increases in response to DNA replication stress; IGD1 has a paralog, YOL024W, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001138.5 Reference assembly

    Range
    182274..182861 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179982.1 → NP_116672.1  TPA: Igd1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_116672.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTP8, P43598
    UniProtKB/TrEMBL
    A7A255, B3LUM6, C7GYC3, C8Z7V2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P43598.1

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