SAP155 Sap155p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: SAP155
Official Full Name: Sap155p
Primary source: SGD:S000001936
Locus tag: YFR040W
See related: AllianceGenome:SGD:S000001936; FungiDB:YFR040W; VEuPathDB:YFR040W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Predicted to enable protein phosphatase regulator activity. Involved in G1/S transition of mitotic cell cycle and negative regulation of potassium ion export across plasma membrane. Predicted to be located in cytoplasm. Predicted to be part of U2-type spliceosomal complex. Predicted to be active in cytosol and nucleus. Orthologous to human PPP6R1 (protein phosphatase 6 regulatory subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome VI - NC_001138.5 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables protein phosphatase binding	IEA Inferred from Electronic Annotation more info
enables protein phosphatase regulator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G1/S transition of mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of potassium ion export across plasma membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of potassium ion export across plasma membrane	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of U2-type spliceosomal complex	ISA Inferred from Sequence Alignment more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

NP_116698.3

Protein required for function of the Sit4p protein phosphatase; forms a complex with Sit4p; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p; protein abundance increases in response to DNA replication stress; SAP155 has a paralog, SAP4, that arose from the whole genome duplication