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BOS1 Bos1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850767, updated on 9-Dec-2024

Summary

Official Symbol
BOS1
Official Full Name
Bos1p
Primary source
SGD:S000004068
Locus tag
YLR078C
See related
AllianceGenome:SGD:S000004068; FungiDB:YLR078C; VEuPathDB:YLR078C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SEC32
Summary
Enables SNAP receptor activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport and vesicle fusion with Golgi apparatus. Located in ER to Golgi transport vesicle membrane and endoplasmic reticulum membrane. Part of SNARE complex. Used to study progressive myoclonus epilepsy 6. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 6. Orthologous to human GOSR2 (golgi SNAP receptor complex member 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See BOS1 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
2
Sequence:
Chromosome: XII; NC_001144.5 (285736..286559, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L10 Neighboring gene Fmp25p Neighboring gene cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1 Neighboring gene Emp46p

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables SNAP receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables SNAP receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle fusion IDA
Inferred from Direct Assay
more info
PubMed 
involved_in vesicle fusion with Golgi apparatus IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in ER to Golgi transport vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in ER to Golgi transport vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of SNARE complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in late endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Bos1p
NP_013179.1
  • v-SNARE (vesicle specific SNAP receptor); localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi; required for efficient nuclear fusion during mating

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    285736..286559 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181965.1NP_013179.1  TPA: Bos1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013179.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VY78, P25385
    UniProtKB/TrEMBL
    A7A0Y2, C8ZD49, G2WIR9
    Conserved Domains (1) summary
    cd15863
    Location:152217
    SNARE_GS27; SNARE motif of GS27